| Field | Specification |
|---|---|
| Target | |
| Antigen | |
| Alternative names | ACTA1;ACTA;Actin, alpha skeletal muscle;Alpha-actin-1 |
| Gene ID | |
| Host | |
| Clone | |
| Clonality | |
| Reactivity | |
| Applications | |
| Immunogen | Synthetic Peptide of α skeletal muscle actin |
| Conjugate | |
| Molecular weight | |
| Purification | |
| Cellular localization | |
| Formulation | |
| Storage | |
| Catalog no. (Mfr.) | |
| Main SKU |
Product Overview
U-Blot® α skeletal muscle actin Mouse Monoclonal Antibody (4B11) is a mouse monoclonal antibody from UcallM Biosciences Inc, raised against Actin skeletal muscle α. It has been validated for Western Blot, Immunohistochemistry, Immunofluorescence, Immunoprecipitation and reacts with Human, Mouse, Rat.
Validated Applications
| Target | Actin skeletal muscle α |
|---|---|
| Host | Mouse |
| Clonality | Monoclonal |
| Clone | 4B11 |
| Conjugate | Unconjugated |
| Reactivity | Human, Mouse, Rat |
| Applications | Western Blot, Immunohistochemistry, Immunofluorescence, Immunoprecipitation |
| Purification | Affinity Purified |
| Specificity | The antibody detects endogenous α Skeletal Muscle Actin protein. |
| Molecular Weight | Observed: 42 kDa |
| UniProt / Swiss-Prot | P68133 (Human) | P68134 (Mouse) | P68136 (Rat) |
Recommended dilutions: WB 1:500-10000;IP 1:200;IF 1:200;IHC 1:50-300
Immunogen / Antigen
Synthetic Peptide of α skeletal muscle actin
Reactivity Notes
Confirmed cross-reactivity: Human, Mouse, Rat. Confirm suitability for untested species before use.
Scientific Background
The product encoded by this gene belongs to the actin family of proteins, which are highly conserved proteins that play a role in cell motility, structure and integrity. Alpha, beta and gamma actin isoforms have been identified, with alpha actins being a major constituent of the contractile apparatus, while beta and gamma actins are involved in the regulation of cell motility. This actin is an alpha actin that is found in skeletal muscle. Mutations in this gene cause nemaline myopathy type 3, congenital myopathy with excess of thin myofilaments, congenital myopathy with cores, and congenital myopathy with fiber-type disproportion, diseases that lead to muscle fiber defects. [provided by RefSeq, Jul 2008]
Safety & Handling
This antibody is validated for Western Blot, Immunohistochemistry, Immunofluorescence, Immunoprecipitation. Recommended dilutions: WB 1:500-10000;IP 1:200;IF 1:200;IHC 1:50-300
Confirmed reactivity: Human, Mouse, Rat. Other species should be validated by the user.
Conjugate: Unconjugated.
Store as follows: -15°C to -25°C/1 year(Do not lower than -25°C)
Clone 4B11.
Customization & Add-ons: Can't find exactly what you need? Contact us for custom formats, conjugations, bulk quantities, or related products.
