| Field | Specification |
|---|---|
| Target | |
| Antigen | |
| Alternative names | ACTA2;ACTSA;ACTVS;GIG46;Actin, aortic smooth muscle;Alpha-actin-2;Cell growth-inhibiting gene 46 protein |
| Gene ID | |
| Host | |
| Clone | |
| Clonality | |
| Reactivity | |
| Applications | |
| Immunogen | Synthetic Peptide of α-SMA |
| Conjugate | |
| Molecular weight | |
| Purification | |
| Cellular localization | |
| Formulation | |
| Storage | |
| Catalog no. (Mfr.) | |
| Main SKU |
Product Overview
U-Blot® α-SMA Mouse Monoclonal Antibody (1E12) is a mouse monoclonal antibody from UcallM Biosciences Inc, raised against Actin_smooth muscle (SMA). It has been validated for Western Blot, Immunohistochemistry and reacts with Human, Mouse, Rat.
Validated Applications
| Target | Actin_smooth muscle (SMA) |
|---|---|
| Host | Mouse |
| Clonality | Monoclonal |
| Clone | 1E12 |
| Conjugate | Unconjugated |
| Reactivity | Human, Mouse, Rat |
| Applications | Western Blot, Immunohistochemistry |
| Purification | Affinity Purified |
| Specificity | The antibody detects endogenous α-SMA protein. |
| Molecular Weight | Observed: 42 kDa |
| UniProt / Swiss-Prot | P62736 (Human) | P62737 (Mouse) | P62738 (Rat) |
Recommended dilutions: WB 1:5000-50000;IHC 1:1000-2000
Immunogen / Antigen
Synthetic Peptide of α-SMA
Reactivity Notes
Confirmed cross-reactivity: Human, Mouse, Rat. Confirm suitability for untested species before use.
Scientific Background
The protein encoded by this gene belongs to the actin family of proteins, which are highly conserved proteins that play a role in cell motility, structure and integrity. Alpha, beta and gamma actin isoforms have been identified, with alpha actins being a major constituent of the contractile apparatus, while beta and gamma actins are involved in the regulation of cell motility. This actin is an alpha actin that is found in skeletal muscle. Defects in this gene cause aortic aneurysm familial thoracic type 6. Multiple alternatively spliced variants, encoding the same protein, have been identified. [provided by RefSeq, Nov 2008]
Safety & Handling
This antibody is validated for Western Blot, Immunohistochemistry. Recommended dilutions: WB 1:5000-50000;IHC 1:1000-2000
Confirmed reactivity: Human, Mouse, Rat. Other species should be validated by the user.
Conjugate: Unconjugated.
Store as follows: -15°C to -25°C/1 year(Do not lower than -25°C)
Clone 1E12.
Customization & Add-ons: Can't find exactly what you need? Contact us for custom formats, conjugations, bulk quantities, or related products.
