| Field | Specification |
|---|---|
| Target | |
| Antigen | |
| Alternative names | AQP4;Aquaporin-4;AQP-4;Mercurial-insensitive water channel;MIWC;WCH4 |
| Gene ID | |
| Host | |
| Clone | |
| Clonality | |
| Reactivity | |
| Applications | |
| Immunogen | Synthetic Peptide of Aquaporin 4 |
| Conjugate | |
| Molecular weight | |
| Purification | |
| Cellular localization | |
| Formulation | |
| Storage | |
| Catalog no. (Mfr.) | |
| Main SKU |
Product Overview
U-Blot® Aquaporin 4 Mouse Monoclonal Antibody (4H1) is a mouse monoclonal antibody from UcallM Biosciences Inc, raised against AQP4. It has been validated for Western Blot, Immunohistochemistry, Immunofluorescence and reacts with Human, Mouse, Rat.
Validated Applications
| Target | AQP4 |
|---|---|
| Host | Mouse |
| Clonality | Monoclonal |
| Clone | 4H1 |
| Conjugate | Unconjugated |
| Reactivity | Human, Mouse, Rat |
| Applications | Western Blot, Immunohistochemistry, Immunofluorescence |
| Purification | Affinity Purified |
| Specificity | The antibody detects endogenous Aquaporin 4 proteins. |
| Molecular Weight | Observed: 48 kDa |
| UniProt / Swiss-Prot | P55087 (Human) | P55088 (Mouse) | P47863 (Rat) |
Recommended dilutions: WB 1:1000;IF 1:100-200;IHC 1:50-300
Immunogen / Antigen
Synthetic Peptide of Aquaporin 4
Reactivity Notes
Confirmed cross-reactivity: Human, Mouse, Rat. Confirm suitability for untested species before use.
Scientific Background
This gene encodes a member of the aquaporin family of intrinsic membrane proteins that function as water-selective channels in the plasma membranes of many cells. This protein is the predominant aquaporin found in brain and has an important role in brain water homeostasis. Alternatively spliced transcript variants encoding different isoforms have been described for this gene. A recent study provided evidence for translational readthrough in this gene and expression of an additional C-terminally extended isoform via the use of an alternative in-frame translation termination codon. [provided by RefSeq, Dec 2015]
Safety & Handling
This antibody is validated for Western Blot, Immunohistochemistry, Immunofluorescence. Recommended dilutions: WB 1:1000;IF 1:100-200;IHC 1:50-300
Confirmed reactivity: Human, Mouse, Rat. Other species should be validated by the user.
Conjugate: Unconjugated.
Store as follows: -15°C to -25°C/1 year(Do not lower than -25°C)
Clone 4H1.
Customization & Add-ons: Can't find exactly what you need? Contact us for custom formats, conjugations, bulk quantities, or related products.
