U-Blot® ARC Rabbit Polyclonal Antibody

SKU:BHA21813959
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    Overview
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    Anti-ARC antibody (Rabbit host, polyclonal, Unconjugated). Validated for Western Blot, ELISA with reactivity to Human, Rat, Mouse.
    Clonality Polyclonal
    Host Rabbit
    Reactivity Human, Rat, Mouse
    Conjugate Unconjugated
    Isotype IgG
    Applications Western Blot, ELISA
    Options selector
    Catalog no. Size
    WP2681-50 50 uL
    WP2681-100 100 uL
    Available Options

    Select the variant that best fits your experiment. Availability and lead time may vary by option.

    • Options: Size: 50 uL
    • Lead time: options listed in "Availability Content"; other statuses may take longer.
    • Storage: -15°C to -25°C/1 year(Do not lower than -25°C)
    • Shipping: cold-chain shipment (typically with ice packs).
    • Upon receipt: store at recommended temperature as soon as possible.
    • Sales terms and conditions: Please review prior to ordering.
    Field Specification
    Antigen
    • Activity-regulated cytoskeleton-associated protein (ARC/ARG3.1) (Activity-regulated gene 3.1 protein homolog) (Arg3.1)
    Cellular Localization Extracellular vesicle membrane ; Lipid-anchor . Cell junction, synapse, postsynaptic cell membrane ; Lipid-anchor . Cell junction, synapse . Cell junction, synapse, postsynaptic density . Early endosome membrane . Cell projection, dendrite . Cytoplasm, cytoskeleton . Cytoplasm, cell cortex . Cell projection, dendritic spine . Cytoplasmic vesicle, secretory vesicle, acrosome . Forms virion-like extracellular vesicles that are released from neurons. Enriched in postsynaptic density of dendritic spines. Targeted to inactive synapses following interaction with CAMK2B in the kinase inactive state. Accumulation at weaker synapses may be required to prevent their undesired enhancement. Associated with the cell cortex of neuronal soma and dendrites (By similarity). Associated with the sperm tail (By similarity). .
    Clonality
    • Polyclonal
    Concentration 1 mg/ml
    Conjugate
    • Unconjugated
    Formulation PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA
    Gene ID 23237 (Human)
    Host Rabbit
    Immunogen Synthesized peptide derived from human protein . at AA range: 70-150
    Isotype
    • IgG
    Molecular Weight Observed: 43 kDa
    Product Type
    • Polyclonal Antibody
    • Primary Antibodies
    Reactivity
    • Human
    • Rat
    • Mouse
    Storage -15°C to -25°C/1 year(Do not lower than -25°C)
    Target ARC
    Antibody

    Product Overview

    U-Blot® ARC Rabbit Polyclonal Antibody is a rabbit polyclonal antibody from UcallM Biosciences Inc, raised against ARC. It has been validated for Western Blot, ELISA and reacts with Human, Rat, Mouse.

    Validated Applications

    Target ARC
    Host Rabbit
    Clonality Polyclonal
    Isotype IgG
    Conjugate Unconjugated
    Reactivity Human, Rat, Mouse
    Applications Western Blot, ELISA
    Purification Affinity Purified
    Specificity ARC Polyclonal Antibody detects endogenous levels of protein.
    Molecular Weight Observed: 43 kDa
    UniProt / Swiss-Prot Q7LC44 (Human) | Q9WV31 (Mouse) | Q63053 (Rat)

    Recommended dilutions: WB 1:500-2000;ELISA 1:5000-20000

    Immunogen / Antigen

    Synthesized peptide derived from human protein . at AA range: 70-150

    Reactivity Notes

    Confirmed cross-reactivity: Human, Rat, Mouse. Confirm suitability for untested species before use.

    Scientific Background

    function:Required for consolidation of synaptic plasticity as well as formation of long-term memory. Regulates endocytosis of AMPA receptors in response to synaptic activity. Required for homeostatic synaptic scaling of AMPA receptors.,similarity:Belongs to the ARC/ARG3.1 family.,subcellular location:Associated with the cell cortex of neuronal soma and dendrites. Enriched in postsynaptic density of dendritic spines. Associated with the sperm tail.,subunit:Interacts with SH3GL1/endophilin-2, SH3GL3/endophilin-3 and DNM2/DYN2.

    Safety & Handling

    For Research Use Only (RUO). Not for diagnostic or therapeutic use. Store as indicated: -15°C to -25°C/1 year(Do not lower than -25°C)
    What applications is this antibody validated for?

    This antibody is validated for Western Blot, ELISA. Recommended dilutions: WB 1:500-2000;ELISA 1:5000-20000

    What species does it react with?

    Confirmed reactivity: Human, Rat, Mouse. Other species should be validated by the user.

    Is this antibody conjugated?

    Conjugate: Unconjugated.

    How should it be stored?

    Store as follows: -15°C to -25°C/1 year(Do not lower than -25°C)

    Customization & Add-ons: Can't find exactly what you need? Contact us for custom formats, conjugations, bulk quantities, or related products.

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