U-Blot® ARK-1 Mouse Monoclonal Antibody (WM0037)

SKU:BHA21801616
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UcallM Biosciences Inc
UcallM Biosciences Inc
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Overview
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Anti-ARK-1 antibody (Mouse host, monoclonal, Unconjugated). Validated for Western Blot, Immunofluorescence, Flow Cytometry, ELISA with reactivity to Human, Rat, Monkey.
Clonality Monoclonal
Host Mouse
Reactivity Human, Rat, Monkey
Conjugate Unconjugated
Applications Western Blot, Immunofluorescence, Flow Cytometry, ELISA
Options selector
Catalog no. Size
WM0037-50 50 uL
WM0037-100 100 uL
Available Options

Select the variant that best fits your experiment. Availability and lead time may vary by option.

  • Options: Size: 50 uL
  • Lead time: options listed in "Availability Content"; other statuses may take longer.
  • Storage: -15°C to -25°C/1 year(Do not lower than -25°C)
  • Shipping: cold-chain shipment (typically with ice packs).
  • Upon receipt: store at recommended temperature as soon as possible.
  • Sales terms and conditions: Please review prior to ordering.
Field Specification
Target ARK-1
Antigen
  • Serine/threonine-protein kinase 6
Alternative names AURKA;AIK;AIRK1;ARK1;AURA;AYK1;BTAK;IAK1;STK15;STK6;Aurora kinase A;Aurora 2;Aurora/IPL1-related kinase 1;ARK-1;Aurora-related kinase 1;hARK1;Breast tumor-amplified kinase;Serine/threonine-protein kinase 15;Serine/threonin
Gene ID 6790 (Human)
Host Mouse
Clonality
  • Monoclonal
Reactivity
  • Human
  • Rat
  • Monkey
Applications
  • Western Blot
  • Immunofluorescence
  • Flow Cytometry
  • ELISA
Immunogen Purified recombinant fragment of human ARK-1 expressed in E. Coli.
Conjugate
  • Unconjugated
Molecular weight Calculated: 46 kDa
Purification Affinity Purified
Cellular localization Cytoplasm, cytoskeleton, microtubule organizing center, centrosome . Cytoplasm, cytoskeleton, spindle pole . Cytoplasm, cytoskeleton, cilium basal body . Cytoplasm, cytoskeleton, microtubule organizing center, centrosome, centriole . Cell projection, neuron projection . Detected at the neurite hillock in developing neurons (By similarity). Localizes at the centrosome in mitotic cells from early prophase until telophase, but also localizes to the spindle pole MTs from prophase to anaphase (PubMed:9606188, PubMed:17229885, PubMed:21225229). Colocalized with SIRT2 at centrosome (PubMed:22014574). Moves to the midbody during both telophase and cytokinesis (PubMed:17726514). Associates with both the pericentriolar material (PCM) and centrioles (PubMed:22014574). The localization to the spindle poles is regulated by AAAS (PubMed:26246606). .
Formulation Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Storage -15°C to -25°C/1 year(Do not lower than -25°C)
Catalog no. (Mfr.) WM0037
Main SKU BHA21801616
Antibody

Product Overview

U-Blot® ARK-1 Mouse Monoclonal Antibody (WM0037) is a mouse monoclonal antibody from UcallM Biosciences Inc, raised against ARK-1. It has been validated for Western Blot, Immunofluorescence, Flow Cytometry, ELISA and reacts with Human, Rat, Monkey.

Validated Applications

Target ARK-1
Host Mouse
Clonality Monoclonal
Conjugate Unconjugated
Reactivity Human, Rat, Monkey
Applications Western Blot, Immunofluorescence, Flow Cytometry, ELISA
Purification Affinity Purified
Specificity ARK-1 Monoclonal Antibody detects endogenous levels of ARK-1 protein.
Molecular Weight Calculated: 46 kDa
UniProt / Swiss-Prot O14965 (Human) | P97477 (Mouse) | P59241 (Rat)

Recommended dilutions: WB 1:500-1:2000;IF 1:200-1:1000;Flow Cyt 1:200-1:400;ELISA 1:10000;Not yet tested in other applications.

Immunogen / Antigen

Purified recombinant fragment of human ARK-1 expressed in E. Coli.

Reactivity Notes

Confirmed cross-reactivity: Human, Rat, Monkey. Confirm suitability for untested species before use.

Scientific Background

The protein encoded by this gene is a cell cycle-regulated kinase that appears to be involved in microtubule formation and/or stabilization at the spindle pole during chromosome segregation. The encoded protein is found at the centrosome in interphase cells and at the spindle poles in mitosis. This gene may play a role in tumor development and progression. A processed pseudogene of this gene has been found on chromosome 1, and an unprocessed pseudogene has been found on chromosome 10. Multiple transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Jul 2008]

Safety & Handling

For Research Use Only (RUO). Not for diagnostic or therapeutic use. Store as indicated: -15°C to -25°C/1 year(Do not lower than -25°C)
What applications is this antibody validated for?

This antibody is validated for Western Blot, Immunofluorescence, Flow Cytometry, ELISA. Recommended dilutions: WB 1:500-1:2000;IF 1:200-1:1000;Flow Cyt 1:200-1:400;ELISA 1:10000;Not yet tested in other applications.

What species does it react with?

Confirmed reactivity: Human, Rat, Monkey. Other species should be validated by the user.

Is this antibody conjugated?

Conjugate: Unconjugated.

How should it be stored?

Store as follows: -15°C to -25°C/1 year(Do not lower than -25°C)

Customization & Add-ons: Can't find exactly what you need? Contact us for custom formats, conjugations, bulk quantities, or related products.

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