| Field | Specification |
|---|---|
| Target | |
| Antigen | |
| Alternative names | ARRB2;ARB2;ARR2;Beta-arrestin-2;Arrestin beta-2 |
| Gene ID | |
| Host | |
| Clonality | |
| Reactivity | |
| Applications | |
| Immunogen | Purified recombinant human Arrestin-β-2 (C-terminus) protein fragments expressed in E.coli. |
| Conjugate | |
| Molecular weight | |
| Purification | |
| Cellular localization | |
| Formulation | |
| Storage | |
| Catalog no. (Mfr.) | |
| Main SKU |
Product Overview
U-Blot® Arrestin-β-2 Mouse Monoclonal Antibody is a mouse monoclonal antibody from UcallM Biosciences Inc, raised against Arrestin-β-2. It has been validated for Western Blot, Immunofluorescence and reacts with Human, Mouse, Rat, Pig.
Validated Applications
| Target | Arrestin-β-2 |
|---|---|
| Host | Mouse |
| Clonality | Monoclonal |
| Conjugate | Unconjugated |
| Reactivity | Human, Mouse, Rat, Pig |
| Applications | Western Blot, Immunofluorescence |
| Purification | Affinity Purified |
| Specificity | Arrestin-β-2 Monoclonal Antibody detects endogenous levels of Arrestin-β-2 protein. |
| Molecular Weight | Calculated: 46 kDa |
| UniProt / Swiss-Prot | P32121 (Human) | Q91YI4 (Mouse) | P29067 (Rat) |
Recommended dilutions: WB 1:1000-1:2000;IF 1:100-1:500;Not yet tested in other applications.
Immunogen / Antigen
Purified recombinant human Arrestin-β-2 (C-terminus) protein fragments expressed in E.coli.
Reactivity Notes
Confirmed cross-reactivity: Human, Mouse, Rat, Pig. Confirm suitability for untested species before use.
Scientific Background
Members of arrestin/beta-arrestin protein family are thought to participate in agonist-mediated desensitization of G-protein-coupled receptors and cause specific dampening of cellular responses to stimuli such as hormones, neurotransmitters, or sensory signals. Arrestin beta 2, like arrestin beta 1, was shown to inhibit beta-adrenergic receptor function in vitro. It is expressed at high levels in the central nervous system and may play a role in the regulation of synaptic receptors. Besides the brain, a cDNA for arrestin beta 2 was isolated from thyroid gland, and thus it may also be involved in hormone-specific desensitization of TSH receptors. Multiple alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Mar 2012]
Safety & Handling
This antibody is validated for Western Blot, Immunofluorescence. Recommended dilutions: WB 1:1000-1:2000;IF 1:100-1:500;Not yet tested in other applications.
Confirmed reactivity: Human, Mouse, Rat, Pig. Other species should be validated by the user.
Conjugate: Unconjugated.
Store as follows: -15°C to -25°C/1 year(Do not lower than -25°C)
Customization & Add-ons: Can't find exactly what you need? Contact us for custom formats, conjugations, bulk quantities, or related products.
