| Field | Specification |
|---|---|
| Target | |
| Antigen | |
| Alternative names | AIE2;AIK3;AIRK3;ARK3;STK13;Aurora kinase C;Aurora 3;Aurora/IPL1 related kinase 3;ARK 3;Aurora related kinase 3;Serine/threonine protein kinase 13;Aurora/IPL1related kinase 3;Aurorarelated kinase 3;Serine/threonineprotein kinase 13;Serine/threonineprotein kinase auroraC |
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| Host | |
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Product Overview
U-Blot® Aurora C Rabbit Monoclonal Antibody is a rabbit monoclonal antibody from UcallM Biosciences Inc, raised against AurC. It has been validated for Western Blot, Immunofluorescence, ELISA and reacts with Human.
Validated Applications
| Target | AurC |
|---|---|
| Host | Rabbit |
| Clonality | Monoclonal |
| Clone | PT1145R |
| Isotype | IgG, Kappa |
| Conjugate | Unconjugated |
| Reactivity | Human |
| Applications | Western Blot, Immunofluorescence, ELISA |
| Purification | Protein A |
| Specificity | Endogenous |
| Molecular Weight | Calculated: 36 kDa | Observed: 36 kDa |
| UniProt / Swiss-Prot | Q9UQB9 (Human) |
Recommended dilutions: WB 1:500-1:2000;IF 1:200-1:1000;ELISA 1:5000-1:20000
Immunogen / Antigen
Serine/threonine-protein kinase 13/Aurora kinase C
Reactivity Notes
Confirmed cross-reactivity: Human. Confirm suitability for untested species before use.
Scientific Background
This gene encodes a member of the Aurora subfamily of serine/threonine protein kinases. The encoded protein is a chromosomal passenger protein that forms complexes with Aurora-B and inner centromere proteins and may play a role in organizing microtubules in relation to centrosome/spindle function during mitosis. This gene is overexpressed in several cancer cell lines, suggesting an involvement in oncogenic signal transduction. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2008]
Safety & Handling
This antibody is validated for Western Blot, Immunofluorescence, ELISA. Recommended dilutions: WB 1:500-1:2000;IF 1:200-1:1000;ELISA 1:5000-1:20000
Confirmed reactivity: Human. Other species should be validated by the user.
Conjugate: Unconjugated.
Store as follows: -15°C to -25°C/1 year(Do not lower than -25°C)
Clone PT1145R.
Customization & Add-ons: Can't find exactly what you need? Contact us for custom formats, conjugations, bulk quantities, or related products.
