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Product Overview
U-Blot® Azurocidin Rabbit Monoclonal Antibody is a rabbit monoclonal antibody from UcallM Biosciences Inc, raised against Azurocidin. It has been validated for Western Blot and reacts with Human.
Validated Applications
| Target | Azurocidin |
|---|---|
| Host | Rabbit |
| Clonality | Monoclonal |
| Clone | PT1131R |
| Isotype | IgG, Kappa |
| Conjugate | Unconjugated |
| Reactivity | Human |
| Applications | Western Blot |
| Purification | Protein A |
| Specificity | Endogenous |
| Molecular Weight | Calculated: 28 kDa | Observed: 28 kDa |
| UniProt / Swiss-Prot | P20160 (Human) |
Recommended dilutions: WB 1:1000-1:5000
Immunogen / Antigen
Azurocidin (Cationic antimicrobial protein CAP37) (Heparin-binding protein) (HBP)
Reactivity Notes
Confirmed cross-reactivity: Human. Confirm suitability for untested species before use.
Scientific Background
Azurophil granules, specialized lysosomes of the neutrophil, contain at least 10 proteins implicated in the killing of microorganisms. This gene encodes a preproprotein that is proteolytically processed to generate a mature azurophil granule antibiotic protein, with monocyte chemotactic and antimicrobial activity. It is also an important multifunctional inflammatory mediator. This encoded protein is a member of the serine protease gene family but it is not a serine proteinase, because the active site serine and histidine residues are replaced. The genes encoding this protein, neutrophil elastase 2, and proteinase 3 are in a cluster located at chromosome 19pter. All 3 genes are expressed coordinately and their protein products are packaged together into azurophil granules during neutrophil differentiation. [provided by RefSeq, Nov 2015]
Safety & Handling
This antibody is validated for Western Blot. Recommended dilutions: WB 1:1000-1:5000
Confirmed reactivity: Human. Other species should be validated by the user.
Conjugate: Unconjugated.
Store as follows: -15°C to -25°C/1 year(Do not lower than -25°C)
Clone PT1131R.
Customization & Add-ons: Can't find exactly what you need? Contact us for custom formats, conjugations, bulk quantities, or related products.
