U-Blot® Beclin-1 (Phospho Ser93/96) Rabbit Polyclonal Antibody

SKU:BHA21805251
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UcallM Biosciences Inc
UcallM Biosciences Inc
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Overview
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Anti-Beclin 1 antibody (Rabbit host, polyclonal, Unconjugated). Validated for Immunohistochemistry, Western Blot with reactivity to Human, Mouse, Rat.
Clonality Polyclonal
Host Rabbit
Reactivity Human, Mouse, Rat
Conjugate Unconjugated
Applications Immunohistochemistry, Western Blot
Options selector
Catalog no. Size
WP10830-50 50 uL
WP10830-100 100 uL
Available Options

Select the variant that best fits your experiment. Availability and lead time may vary by option.

  • Options: Size: 50 uL
  • Lead time: options listed in "Availability Content"; other statuses may take longer.
  • Storage: -15°C to -25°C/1 year(Do not lower than -25°C)
  • Shipping: cold-chain shipment (typically with ice packs).
  • Upon receipt: store at recommended temperature as soon as possible.
  • Sales terms and conditions: Please review prior to ordering.
Field Specification
Target Beclin 1
Antigen
  • Beclin-1 (Coiled-coil myosin-like BCL2-interacting protein) (Protein GT197)
Alternative names Beclin-1;Coiled-coil myosin-like BCL2-interacting protein;Protein GT197
Gene ID 8678 (Human) | 56208 (Mouse) | 114558 (Rat)
Host Rabbit
Clonality
  • Polyclonal
Reactivity
  • Human
  • Mouse
  • Rat
Applications
  • Immunohistochemistry
  • Western Blot
Immunogen Synthesized peptide derived from human Beclin-1 (Phospho Ser93/96)
Conjugate
  • Unconjugated
Molecular weight Observed: 55 kDa
Purification Affinity Purified
Cellular localization Cytoplasm . Golgi apparatus, trans-Golgi network membrane ; Peripheral membrane protein . Endosome membrane ; Peripheral membrane protein . Endoplasmic reticulum membrane ; Peripheral membrane protein . Mitochondrion membrane ; Peripheral membrane protein . Endosome . Cytoplasmic vesicle, autophagosome . Interaction with ATG14 promotes translocation to autophagosomes. Expressed in dendrites and cell bodies of cerebellar Purkinje cells (By similarity). .; [Beclin-1-C 35 kDa]: Mitochondrion . Nucleus . Cytoplasm .; [Beclin-1-C 37 kDa]: Mitochondrion .
Concentration 1 mg/ml
Formulation PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA
Storage -15°C to -25°C/1 year(Do not lower than -25°C)
Catalog no. (Mfr.) WP10830
Main SKU BHA21805251
Antibody

Product Overview

U-Blot® Beclin-1 (Phospho Ser93/96) Rabbit Polyclonal Antibody is a rabbit polyclonal antibody from UcallM Biosciences Inc, raised against Beclin 1. Recognizes Phospho. It has been validated for Immunohistochemistry, Western Blot and reacts with Human, Mouse, Rat.

Validated Applications

Target Beclin 1
Host Rabbit
Clonality Polyclonal
Conjugate Unconjugated
Reactivity Human, Mouse, Rat
Applications Immunohistochemistry, Western Blot
Purification Affinity Purified
Specificity This antibody detects endogenous levels of Beclin-1 (Phospho Ser93/96) Rabbit pAb at Human, Mouse,Rat
Molecular Weight Observed: 55 kDa
UniProt / Swiss-Prot Q14457 (Human) | O88597 (Mouse) | Q91XJ1 (Rat)

Recommended dilutions: WB 1:500-2000;IHC 1:50-200

Immunogen / Antigen

Synthesized peptide derived from human Beclin-1 (Phospho Ser93/96)

Reactivity Notes

Confirmed cross-reactivity: Human, Mouse, Rat. Confirm suitability for untested species before use.

Scientific Background

beclin 1(BECN1) Homo sapiens This gene encodes a protein that regulates autophagy, a catabolic process of degradation induced by starvation. The encoded protein is a component of the phosphatidylinositol-3-kinase (PI3K) complex which mediates vesicle-trafficking processes. This protein is thought to play a role in multiple cellular processes, including tumorigenesis, neurodegeneration and apoptosis. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Sep 2015]

Safety & Handling

For Research Use Only (RUO). Not for diagnostic or therapeutic use. Store as indicated: -15°C to -25°C/1 year(Do not lower than -25°C)
What applications is this antibody validated for?

This antibody is validated for Immunohistochemistry, Western Blot. Recommended dilutions: WB 1:500-2000;IHC 1:50-200

What species does it react with?

Confirmed reactivity: Human, Mouse, Rat. Other species should be validated by the user.

Is this antibody conjugated?

Conjugate: Unconjugated.

How should it be stored?

Store as follows: -15°C to -25°C/1 year(Do not lower than -25°C)

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