U-Blot® Beclin-1 Rabbit Polyclonal Antibody

SKU:BHA21810650
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UcallM Biosciences Inc
UcallM Biosciences Inc
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Overview
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Anti-Beclin 1 antibody (Rabbit host, polyclonal, Unconjugated). Validated for Western Blot, ELISA with reactivity to Human, Mouse, Chicken.
Clonality Polyclonal
Host Rabbit
Reactivity Human, Mouse, Chicken
Conjugate Unconjugated
Isotype IgG
Applications Western Blot, ELISA
Options selector
Catalog no. Size
WP15738-50 50 uL
WP15738-100 100 uL
Available Options

Select the variant that best fits your experiment. Availability and lead time may vary by option.

  • Options: Size: 50 uL
  • Lead time: options listed in "Availability Content"; other statuses may take longer.
  • Storage: -15°C to -25°C/1 year(Do not lower than -25°C)
  • Shipping: cold-chain shipment (typically with ice packs).
  • Upon receipt: store at recommended temperature as soon as possible.
  • Sales terms and conditions: Please review prior to ordering.
Field Specification
Target Beclin 1
Antigen
  • Beclin-1
Alternative names beclin 1, autophagy related
Gene ID 8678 (Human) | 56208 (Mouse)
Host Rabbit
Clonality
  • Polyclonal
Isotype
  • IgG
Reactivity
  • Human
  • Mouse
  • Chicken
Applications
  • Western Blot
  • ELISA
Immunogen Synthesized peptide derived from Beclin-1 . at AA range: 110-190
Conjugate
  • Unconjugated
Molecular weight Observed: 55 kDa
Purification Affinity Purified
Cellular localization Cytoplasm . Golgi apparatus, trans-Golgi network membrane ; Peripheral membrane protein . Endosome membrane ; Peripheral membrane protein . Endoplasmic reticulum membrane ; Peripheral membrane protein . Mitochondrion membrane ; Peripheral membrane protein . Endosome . Cytoplasmic vesicle, autophagosome . Interaction with ATG14 promotes translocation to autophagosomes. Expressed in dendrites and cell bodies of cerebellar Purkinje cells (By similarity). .; [Beclin-1-C 35 kDa]: Mitochondrion . Nucleus . Cytoplasm .; [Beclin-1-C 37 kDa]: Mitochondrion .
Concentration 1 mg/ml
Formulation Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Storage -15°C to -25°C/1 year(Do not lower than -25°C)
Catalog no. (Mfr.) WP15738
Main SKU BHA21810650
Antibody

Product Overview

U-Blot® Beclin-1 Rabbit Polyclonal Antibody is a rabbit polyclonal antibody from UcallM Biosciences Inc, raised against Beclin 1. It has been validated for Western Blot, ELISA and reacts with Human, Mouse, Chicken.

Validated Applications

Target Beclin 1
Host Rabbit
Clonality Polyclonal
Isotype IgG
Conjugate Unconjugated
Reactivity Human, Mouse, Chicken
Applications Western Blot, ELISA
Purification Affinity Purified
Specificity Beclin-1 Polyclonal Antibody detects endogenous levels of Beclin-1
Molecular Weight Observed: 55 kDa
UniProt / Swiss-Prot Q14457 (Human) | O88597 (Mouse)

Recommended dilutions: WB 1:500-2000;ELISA 1:10000-20000

Immunogen / Antigen

Synthesized peptide derived from Beclin-1 . at AA range: 110-190

Reactivity Notes

Confirmed cross-reactivity: Human, Mouse, Chicken. Confirm suitability for untested species before use.

Scientific Background

beclin 1(BECN1) Homo sapiens This gene encodes a protein that regulates autophagy, a catabolic process of degradation induced by starvation. The encoded protein is a component of the phosphatidylinositol-3-kinase (PI3K) complex which mediates vesicle-trafficking processes. This protein is thought to play a role in multiple cellular processes, including tumorigenesis, neurodegeneration and apoptosis. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Sep 2015]

Safety & Handling

For Research Use Only (RUO). Not for diagnostic or therapeutic use. Store as indicated: -15°C to -25°C/1 year(Do not lower than -25°C)
What applications is this antibody validated for?

This antibody is validated for Western Blot, ELISA. Recommended dilutions: WB 1:500-2000;ELISA 1:10000-20000

What species does it react with?

Confirmed reactivity: Human, Mouse, Chicken. Other species should be validated by the user.

Is this antibody conjugated?

Conjugate: Unconjugated.

How should it be stored?

Store as follows: -15°C to -25°C/1 year(Do not lower than -25°C)

Customization & Add-ons: Can't find exactly what you need? Contact us for custom formats, conjugations, bulk quantities, or related products.

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