| Field | Specification |
|---|---|
| Target | |
| Antigen | |
| Alternative names | Target of rapamycin complex subunit LST8;TORC subunit LST8;G protein beta subunit-like;Gable;Protein GbetaL;Mammalian lethal with SEC13 protein 8;mLST8 |
| Gene ID | |
| Host | |
| Clonality | |
| Isotype | |
| Reactivity | |
| Applications | |
| Immunogen | Synthesized peptide derived from human BNP AA range: 89-139 |
| Conjugate | |
| Molecular weight | |
| Purification | |
| Cellular localization | |
| Concentration | |
| Formulation | |
| Storage | |
| Catalog no. (Mfr.) | |
| Main SKU |
Product Overview
U-Blot® BNP Rabbit Polyclonal Antibody is a rabbit polyclonal antibody from UcallM Biosciences Inc, raised against BNP. It has been validated for Immunohistochemistry and reacts with Human.
Validated Applications
| Target | BNP |
|---|---|
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugate | Unconjugated |
| Reactivity | Human |
| Applications | Immunohistochemistry |
| Purification | Affinity Purified |
| Specificity | This antibody detects endogenous levels of BNP at Human |
| Molecular Weight | Observed: 37 kDa |
| UniProt / Swiss-Prot | Q9BVC4 (Human) | Q9DCJ1 (Mouse) | Q9Z2K5 (Rat) |
Recommended dilutions: IHC 1:50-200
Immunogen / Antigen
Synthesized peptide derived from human BNP AA range: 89-139
Reactivity Notes
Confirmed cross-reactivity: Human. Confirm suitability for untested species before use.
Scientific Background
Natriuretic peptide B(NPPB) Homo sapiens This gene is a member of the natriuretic peptide family and encodes a secreted protein which functions as a cardiac hormone. The protein undergoes two cleavage events, one within the cell and a second after secretion into the blood. The protein's biological actions include natriuresis, diuresis, vasorelaxation, inhibition of renin and aldosterone secretion, and a key role in cardiovascular homeostasis. A high concentration of this protein in the bloodstream is indicative of heart failure. The protein also acts as an antimicrobial peptide with antibacterial and antifungal activity. Mutations in this gene have been associated with postmenopausal osteoporosis.
Safety & Handling
This antibody is validated for Immunohistochemistry. Recommended dilutions: IHC 1:50-200
Confirmed reactivity: Human. Other species should be validated by the user.
Conjugate: Unconjugated.
Store as follows: -15°C to -25°C/1 year(Do not lower than -25°C)
Customization & Add-ons: Can't find exactly what you need? Contact us for custom formats, conjugations, bulk quantities, or related products.
