| Field | Specification |
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| Reactivity | |
| Applications | |
| Immunogen | Synthesized peptide derived from human BOB.1 AA range: 150-256 |
| Conjugate | |
| Molecular weight | |
| Purification | |
| Cellular localization | |
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Product Overview
U-Blot® BOB.1 (ABT-BOB1) Mouse Monoclonal Antibody (WM1574) is a mouse monoclonal antibody from UcallM Biosciences Inc, raised against BOB.1. It has been validated for Immunohistochemistry, ELISA and reacts with Human, Mouse.
Validated Applications
| Target | BOB.1 |
|---|---|
| Host | Mouse |
| Clonality | Monoclonal |
| Clone | ABT-BOB1 |
| Isotype | IgG2a, Kappa |
| Conjugate | Unconjugated |
| Reactivity | Human, Mouse |
| Applications | Immunohistochemistry, ELISA |
| Purification | Affinity Purified |
| Specificity | The antibody can specifically recognize human BOB.1 protein. |
| Molecular Weight | Calculated: 27 kDa | Observed: 35 kDa |
| UniProt / Swiss-Prot | Q16633 (Human) |
Recommended dilutions: IHC 1:50-200;ELISA 1:500-5000
Immunogen / Antigen
Synthesized peptide derived from human BOB.1 AA range: 150-256
Reactivity Notes
Confirmed cross-reactivity: Human, Mouse. Confirm suitability for untested species before use.
Scientific Background
disease:A chromosomal aberration involving POU2AF1/OBF1 may be a cause of a form of B-cell leukemia. Translocation t(3;11)(q27;q23) with BCL6.,function:Transcriptional coactivator that specifically associates with either OCT1 or OCT2. It boosts the OCT1 mediated promoter activity and to a lesser extent, that of OCT2. It has no intrinsic DNA-binding activity. It recognizes the POU domains of OCT1 and OCT2. It is essential for the response of B-cells to antigens and required for the formation of germinal centers.,PTM:Ubiquitinated; mediated by SIAH1 or SIAH2 and leading to its subsequent proteasomal degradation.,similarity:Belongs to the POU2AF1 family.,tissue specificity:B-cell specific.
Safety & Handling
This antibody is validated for Immunohistochemistry, ELISA. Recommended dilutions: IHC 1:50-200;ELISA 1:500-5000
Confirmed reactivity: Human, Mouse. Other species should be validated by the user.
Conjugate: Unconjugated.
Store as follows: -15°C to -25°C/1 year(Do not lower than -25°C)
Clone ABT-BOB1.
Customization & Add-ons: Can't find exactly what you need? Contact us for custom formats, conjugations, bulk quantities, or related products.
