U-Blot® c-Fes (Phospho Tyr713) Rabbit Polyclonal Antibody

SKU:BHA21805096
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UcallM Biosciences Inc
UcallM Biosciences Inc
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Overview
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Anti-c-Fes antibody (Rabbit host, polyclonal, Unconjugated). Validated for Western Blot with reactivity to Human, Mouse, Rat.
Clonality Polyclonal
Host Rabbit
Reactivity Human, Mouse, Rat
Conjugate Unconjugated
Isotype IgG
Applications Western Blot
Options selector
Catalog no. Size
WP10689-50 50 uL
WP10689-100 100 uL
Available Options

Select the variant that best fits your experiment. Availability and lead time may vary by option.

  • Options: Size: 50 uL
  • Lead time: options listed in "Availability Content"; other statuses may take longer.
  • Storage: -15°C to -25°C/1 year(Do not lower than -25°C)
  • Shipping: cold-chain shipment (typically with ice packs).
  • Upon receipt: store at recommended temperature as soon as possible.
  • Sales terms and conditions: Please review prior to ordering.
Field Specification
Target c-Fes
Antigen
  • c-Fes (Phospho-Tyr713)
Alternative names Tyrosine-protein kinase Fes/Fps;Feline sarcoma/Fujinami avian sarcoma oncogene homolog;Proto-oncogene c-Fes;Proto-oncogene c-Fps;p93c-fes
Gene ID 2242 (Human) | 14159 (Mouse)
Host Rabbit
Clonality
  • Polyclonal
Isotype
  • IgG
Reactivity
  • Human
  • Mouse
  • Rat
Applications
  • Western Blot
Immunogen Synthesized peptide derived from human c-Fes (Phospho-Tyr713)
Conjugate
  • Unconjugated
Molecular weight Calculated: 90 kDa
Purification Affinity Purified
Cellular localization Cytoplasm, cytosol. Cytoplasm, cytoskeleton. Cell membrane; Peripheral membrane protein; Cytoplasmic side. Cytoplasmic vesicle. Golgi apparatus. Cell junction, focal adhesion. Distributed throughout the cytosol when the kinase is not activated. Association with microtubules requires activation of the kinase activity. Shuttles between focal adhesions and cell-cell contacts in epithelial cells. Recruited to the lateral cell membrane in polarized epithelial cells by interaction with phosphorylated EZR. Detected at tubular membrane structures in the cytoplasm and at the cell periphery.
Concentration 1 mg/ml
Formulation Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Storage -15°C to -25°C/1 year(Do not lower than -25°C)
Catalog no. (Mfr.) WP10689
Main SKU BHA21805096
Antibody

Product Overview

U-Blot® c-Fes (Phospho Tyr713) Rabbit Polyclonal Antibody is a rabbit polyclonal antibody from UcallM Biosciences Inc, raised against c-Fes. Recognizes Phospho. It has been validated for Western Blot and reacts with Human, Mouse, Rat.

Validated Applications

Target c-Fes
Host Rabbit
Clonality Polyclonal
Isotype IgG
Conjugate Unconjugated
Reactivity Human, Mouse, Rat
Applications Western Blot
Purification Affinity Purified
Specificity This antibody detects endogenous levels of c-Fes (Phospho-Tyr713) at Human, Mouse,Rat
Molecular Weight Calculated: 90 kDa
UniProt / Swiss-Prot P07332 (Human) | P16879 (Mouse)

Recommended dilutions: WB 1:500-2000

Immunogen / Antigen

Synthesized peptide derived from human c-Fes (Phospho-Tyr713)

Reactivity Notes

Confirmed cross-reactivity: Human, Mouse, Rat. Confirm suitability for untested species before use.

Scientific Background

This gene encodes the human cellular counterpart of a feline sarcoma retrovirus protein with transforming capabilities. The gene product has tyrosine-specific protein kinase activity and that activity is required for maintenance of cellular transformation. Its chromosomal location has linked it to a specific translocation event identified in patients with acute promyelocytic leukemia but it is also involved in normal hematopoiesis as well as growth factor and cytokine receptor signaling. Alternative splicing results in multiple variants encoding different isoforms.[provided by RefSeq, Jan 2009]

Safety & Handling

For Research Use Only (RUO). Not for diagnostic or therapeutic use. Store as indicated: -15°C to -25°C/1 year(Do not lower than -25°C)
What applications is this antibody validated for?

This antibody is validated for Western Blot. Recommended dilutions: WB 1:500-2000

What species does it react with?

Confirmed reactivity: Human, Mouse, Rat. Other species should be validated by the user.

Is this antibody conjugated?

Conjugate: Unconjugated.

How should it be stored?

Store as follows: -15°C to -25°C/1 year(Do not lower than -25°C)

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