| Field | Specification |
|---|---|
| Target | |
| Antigen | |
| Alternative names | CFLAR;CASH;CASP8AP1;CLARP;MRIT;CASP8 and FADD-like apoptosis regulator;Caspase homolog;CASH;Caspase-eight-related protein;Casper;Caspase-like apoptosis regulatory protein;CLARP;Cellular FLICE-like inhibitory protein;c-FLIP;FADD-like antiapoptotic molecule 1;FLAME-1;Inhibitor of FLICE;I-FLICE;MACH-related inducer of toxicity;MRIT;Usurpin |
| Gene ID | |
| Host | |
| Clonality | |
| Isotype | |
| Reactivity | |
| Applications | |
| Immunogen | The antiserum was produced against synthesized peptide derived from the N-terminal region of human CFLAR. AA range:1-50 |
| Conjugate | |
| Molecular weight | |
| Purification | |
| Cellular localization | |
| Concentration | |
| Formulation | |
| Storage | |
| Catalog no. (Mfr.) | |
| Main SKU |
Product Overview
U-Blot® c-FLIP Rabbit Polyclonal Antibody (WP15238) is a rabbit polyclonal antibody from UcallM Biosciences Inc, raised against c-FLIP. It has been validated for Western Blot, ELISA and reacts with Human, Mouse.
Validated Applications
| Target | c-FLIP |
|---|---|
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugate | Unconjugated |
| Reactivity | Human, Mouse |
| Applications | Western Blot, ELISA |
| Purification | Affinity Purified |
| Specificity | c-FLIP Polyclonal Antibody detects endogenous levels of c-FLIP protein. |
| Molecular Weight | Observed: 55 kDa |
| UniProt / Swiss-Prot | O15519 (Human) | O35732 (Mouse) |
Recommended dilutions: WB 1:500-1:2000;ELISA 1:20000;Not yet tested in other applications.
Immunogen / Antigen
The antiserum was produced against synthesized peptide derived from the N-terminal region of human CFLAR. AA range:1-50
Reactivity Notes
Confirmed cross-reactivity: Human, Mouse. Confirm suitability for untested species before use.
Scientific Background
The protein encoded by this gene is a regulator of apoptosis and is structurally similar to caspase-8. However, the encoded protein lacks caspase activity and appears to be itself cleaved into two peptides by caspase-8. Several transcript variants encoding different isoforms have been found for this gene, and partial evidence for several more variants exists. [provided by RefSeq, Feb 2011]
Safety & Handling
This antibody is validated for Western Blot, ELISA. Recommended dilutions: WB 1:500-1:2000;ELISA 1:20000;Not yet tested in other applications.
Confirmed reactivity: Human, Mouse. Other species should be validated by the user.
Conjugate: Unconjugated.
Store as follows: -15°C to -25°C/1 year(Do not lower than -25°C)
Customization & Add-ons: Can't find exactly what you need? Contact us for custom formats, conjugations, bulk quantities, or related products.
