| Field | Specification |
|---|---|
| Target | |
| Antigen | |
| Alternative names | MME;EPN;Neprilysin;Atriopeptidase;Common acute lymphocytic leukemia antigen;CALLA;Enkephalinase;Neutral endopeptidase 24.11;NEP;Neutral endopeptidase;Skin fibroblast elastase;SFE;CD10 |
| Gene ID | |
| Host | |
| Clone | |
| Clonality | |
| Reactivity | |
| Applications | |
| Immunogen | Synthetic Peptide of CD10 |
| Conjugate | |
| Molecular weight | |
| Purification | |
| Cellular localization | |
| Formulation | |
| Storage | |
| Catalog no. (Mfr.) | |
| Main SKU |
Product Overview
U-Blot® CD10 Mouse Monoclonal Antibody (5B8) is a mouse monoclonal antibody from UcallM Biosciences Inc, raised against CD10. It has been validated for Immunofluorescence, Immunohistochemistry and reacts with Human, Mouse, Rat.
Validated Applications
| Target | CD10 |
|---|---|
| Host | Mouse |
| Clonality | Monoclonal |
| Clone | 5B8 |
| Conjugate | Unconjugated |
| Reactivity | Human, Mouse, Rat |
| Applications | Immunofluorescence, Immunohistochemistry |
| Purification | Affinity Purified |
| Specificity | The antibody detects endogenous CD10 proteins. |
| Molecular Weight | Calculated: 86 kDa |
| UniProt / Swiss-Prot | P08473 (Human) | Q61391 (Mouse) | P07861 (Rat) |
Recommended dilutions: IF 1:50-200;IHC 1:50-200
Immunogen / Antigen
Synthetic Peptide of CD10
Reactivity Notes
Confirmed cross-reactivity: Human, Mouse, Rat. Confirm suitability for untested species before use.
Scientific Background
This gene encodes a common acute lymphocytic leukemia antigen that is an important cell surface marker in the diagnosis of human acute lymphocytic leukemia (ALL). This protein is present on leukemic cells of pre-B phenotype, which represent 85% of cases of ALL. This protein is not restricted to leukemic cells, however, and is found on a variety of normal tissues. It is a glycoprotein that is particularly abundant in kidney, where it is present on the brush border of proximal tubules and on glomerular epithelium. The protein is a neutral endopeptidase that cleaves peptides at the amino side of hydrophobic residues and inactivates several peptide hormones including glucagon, enkephalins, substance P, neurotensin, oxytocin, and bradykinin. This gene, which encodes a 100-kD type II transmembrane glycoprotein, exists in a single copy of greater than 45 kb. The 5' untranslated region of this
Safety & Handling
This antibody is validated for Immunofluorescence, Immunohistochemistry. Recommended dilutions: IF 1:50-200;IHC 1:50-200
Confirmed reactivity: Human, Mouse, Rat. Other species should be validated by the user.
Conjugate: Unconjugated.
Store as follows: -15°C to -25°C/1 year(Do not lower than -25°C)
Clone 5B8.
Customization & Add-ons: Can't find exactly what you need? Contact us for custom formats, conjugations, bulk quantities, or related products.
