| Field | Specification |
|---|---|
| Target | |
| Antigen | |
| Alternative names | Mast/stem cell growth factor receptor Kit;SCFR;Piebald trait protein;PBT;Proto-oncogene c-Kit;Tyrosine-protein kinase Kit;p145 c-kit;v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog;CD antigen CD117 |
| Gene ID | |
| Host | |
| Clone | |
| Clonality | |
| Isotype | |
| Reactivity | |
| Applications | |
| Immunogen | Synthesized peptide derived from human CD117 (C-kit) AA range: 300-400 |
| Conjugate | |
| Molecular weight | |
| Purification | |
| Cellular localization | |
| Formulation | |
| Storage | |
| Catalog no. (Mfr.) | |
| Main SKU |
Product Overview
U-Blot® CD117 (C-kit) (ABT233) Mouse Monoclonal Antibody (WM1756) is a mouse monoclonal antibody from UcallM Biosciences Inc, raised against c-Kit/CD117. It has been validated for Immunohistochemistry, ELISA and reacts with Human.
Validated Applications
| Target | c-Kit/CD117 |
|---|---|
| Host | Mouse |
| Clonality | Monoclonal |
| Clone | ABT233 |
| Isotype | IgG2b, Kappa |
| Conjugate | Unconjugated |
| Reactivity | Human |
| Applications | Immunohistochemistry, ELISA |
| Purification | Affinity Purified |
| Specificity | The antibody can specifically recognize human CD117 protein. |
| Molecular Weight | Calculated: 120 kDa | Observed: 150 kDa |
| UniProt / Swiss-Prot | P10721 (Human) |
Recommended dilutions: IHC 1:50-200;ELISA 1:500-5000
Immunogen / Antigen
Synthesized peptide derived from human CD117 (C-kit) AA range: 300-400
Reactivity Notes
Confirmed cross-reactivity: Human. Confirm suitability for untested species before use.
Scientific Background
This gene encodes the human homolog of the proto-oncogene c-kit. C-kit was first identified as the cellular homolog of the feline sarcoma viral oncogene v-kit. This protein is a type 3 transmembrane receptor for MGF (mast cell growth factor, also known as stem cell factor). Mutations in this gene are associated with gastrointestinal stromal tumors, mast cell disease, acute myelogenous lukemia, and piebaldism. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
Safety & Handling
This antibody is validated for Immunohistochemistry, ELISA. Recommended dilutions: IHC 1:50-200;ELISA 1:500-5000
Confirmed reactivity: Human. Other species should be validated by the user.
Conjugate: Unconjugated.
Store as follows: -15°C to -25°C/1 year(Do not lower than -25°C)
Clone ABT233.
Customization & Add-ons: Can't find exactly what you need? Contact us for custom formats, conjugations, bulk quantities, or related products.
