| Field | Specification |
|---|---|
| Alternative Names | C Kit;c-Kit;c-Kit Ligand;CD117;Kit;Kit Ligand;KIT oncogene;KIT proto oncogene receptor tyrosine kinase;KIT_HUMAN;Mast cell growth factor receptor;Mast/stem cell growth factor receptor Kit;MGF;p145 c-kit;PBT;Piebald trait protein;Proto oncogene c Kit;Proto oncogene tyrosine protein kinase Kit;Proto-oncogene c-Kit;SCF Receptor;SCFR;soluble KIT variant 1;Steel Factor Receptor;Stem cell factor receptor;tyrosine protein kinase Kit;Tyrosine-protein kinase Kit;v kit Hardy Zuckerman 4 feline sarcoma viral oncogene homolog;v kit Hardy Zuckerman 4 feline sarcoma viral oncogene like protein;v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog |
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Product Overview
U-Blot® CD117/c-Kit Rabbit Monoclonal Antibody is a rabbit monoclonal antibody from UcallM Biosciences Inc, raised against c Kit/CD117. It has been validated for Western Blot, Immunofluorescence, Immunoprecipitation, ELISA and reacts with Human, Mouse.
Validated Applications
| Target | c Kit/CD117 |
|---|---|
| Host | Rabbit |
| Clonality | Monoclonal |
| Clone | PT0818R |
| Isotype | IgG, Kappa |
| Conjugate | Unconjugated |
| Reactivity | Human, Mouse |
| Applications | Western Blot, Immunofluorescence, Immunoprecipitation, ELISA |
| Purification | Protein A |
| Specificity | Endogenous |
| Molecular Weight | Calculated: 110 kDa | Observed: 130 kDa |
| UniProt / Swiss-Prot | P10721 (Human) | P05532 (Mouse) |
Recommended dilutions: WB 1:500-1:2000;IF 1:200-1:1000;ELISA 1:5000-1:20000;IP 1:50-1:200
Immunogen / Antigen
C Kit;c-Kit;c-Kit Ligand;CD117;Kit;Kit Ligand;KIT oncogene;KIT proto oncogene receptor tyrosine kinase;KIT_HUMAN;Mast cell growth factor receptor;Mast/stem cell growth factor receptor Kit;MGF;p145 c-kit;PBT;Piebald trait protein;Proto oncogene c Kit;Proto oncogene tyrosine protein kinase Kit;Proto-oncogene c-Kit;SCF Receptor;SCFR;soluble KIT variant 1;Steel Factor Receptor;Stem cell factor receptor;tyrosine protein kinase Kit;Tyrosine-protein kinase Kit;v kit Hardy Zuckerman 4 feline sarcoma viral oncogene homolog;v kit Hardy Zuckerman 4 feline sarcoma viral oncogene like protein;v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog
Reactivity Notes
Confirmed cross-reactivity: Human, Mouse. Confirm suitability for untested species before use.
Scientific Background
This gene encodes the human homolog of the proto-oncogene c-kit. C-kit was first identified as the cellular homolog of the feline sarcoma viral oncogene v-kit. This protein is a type 3 transmembrane receptor for MGF (mast cell growth factor, also known as stem cell factor). Mutations in this gene are associated with gastrointestinal stromal tumors, mast cell disease, acute myelogenous lukemia, and piebaldism. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
Safety & Handling
This antibody is validated for Western Blot, Immunofluorescence, Immunoprecipitation, ELISA. Recommended dilutions: WB 1:500-1:2000;IF 1:200-1:1000;ELISA 1:5000-1:20000;IP 1:50-1:200
Confirmed reactivity: Human, Mouse. Other species should be validated by the user.
Conjugate: Unconjugated.
Store as follows: -15°C to -25°C/1 year(Do not lower than -25°C)
Clone PT0818R.
Customization & Add-ons: Can't find exactly what you need? Contact us for custom formats, conjugations, bulk quantities, or related products.
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