| Field | Specification |
|---|---|
| Target | |
| Antigen | |
| Alternative names | CD 27 antibody;CD27 antibody;CD27 antigen antibody;CD27 molecule antibody;CD27_HUMAN antibody;CD27L receptor antibody;LPFS2 antibody;MGC20393 antibody;OTTHUMP00000238557 antibody;S152 antibody;T cell activation antigen CD27 antibody;T cell antivation antigen S152 antibody;T-cell activation antigen CD27 antibody;T14 antibody;TNFRSF 7 antibody;TNFRSF7 antibody;TNFSF7 antibody;Tp 55 antibody;Tp55 antibody;Tumor necrosis factor receptor superfamily member 7 antibody;CD27 nanobody |
| Gene ID | |
| Host | |
| Clone | |
| Clonality | |
| Isotype | |
| Reactivity | |
| Applications | |
| Immunogen | Purified recombinant Human CD27 |
| Conjugate | |
| Purification | |
| Cellular localization | |
| Concentration | |
| Formulation | |
| Storage | |
| Catalog no. (Mfr.) | |
| Main SKU |
Product Overview
U-Blot® CD27 (PTR1377) recombinant Mouse Monoclonal Antibody is a mouse monoclonal antibody from UcallM Biosciences Inc, raised against CD27. It has been validated for Flow Cytometry, ELISA and reacts with Human.
Validated Applications
| Target | CD27 |
|---|---|
| Host | Mouse |
| Clonality | Monoclonal |
| Clone | PTR1377 |
| Isotype | IgG1, Kappa |
| Conjugate | Unconjugated |
| Reactivity | Human |
| Applications | Flow Cytometry, ELISA |
| Purification | Affinity Purified |
| Specificity | This recombinant monoclonal antibody can detects endogenous levels of CD27 protein. |
| UniProt / Swiss-Prot | P26842 (Human) |
Recommended dilutions: ELISA 1:5000-100000;Flow Cyt 1-2μg/Test
Immunogen / Antigen
Purified recombinant Human CD27
Reactivity Notes
Confirmed cross-reactivity: Human. Confirm suitability for untested species before use.
Scientific Background
CD27 molecule(CD27) Homo sapiens The protein encoded byThis gene is a member of the TNF-receptor superfamily.This receptor is required for generation and long-term maintenance of T cell immunity. It binds to ligand CD70, and plays a key role in regulating B-cell activation and immunoglobulin synthesis.This receptor transduces signals that lead to the activation of NF-kappaB and MAPK8/JNK. Adaptor proteins TRAF2 and TRAF5 have been shown to mediate the signaling process ofThis receptor. CD27-binding protein (SIVA), a proapoptotic protein, can bind toThis receptor and is thought to play an important role in the apoptosis induced byThis receptor. [provided by RefSeq, Jul 2008]
Safety & Handling
This antibody is validated for Flow Cytometry, ELISA. Recommended dilutions: ELISA 1:5000-100000;Flow Cyt 1-2μg/Test
Confirmed reactivity: Human. Other species should be validated by the user.
Conjugate: Unconjugated.
Store as follows: -15°C to -25°C/1 year(Avoid freeze / thaw cycles)
Clone PTR1377.
Customization & Add-ons: Can't find exactly what you need? Contact us for custom formats, conjugations, bulk quantities, or related products.
