| Field | Specification |
|---|---|
| Target | |
| Antigen | |
| Alternative names | T-cell surface glycoprotein CD3 epsilon chain;T-cell surface antigen T3/Leu-4 epsilon chain;CD antigen CD3e;CD3 nanobody |
| Gene ID | |
| Host | |
| Clone | |
| Clonality | |
| Isotype | |
| Reactivity | |
| Applications | |
| Immunogen | Purified recombinant Human CD3 |
| Conjugate | |
| Purification | |
| Cellular localization | |
| Concentration | |
| Formulation | |
| Storage | |
| Catalog no. (Mfr.) | |
| Main SKU |
Product Overview
U-Blot® CD3 (PTR1374) recombinant Mouse Monoclonal Antibody is a mouse monoclonal antibody from UcallM Biosciences Inc, raised against CD3. It has been validated for Flow Cytometry, ELISA and reacts with Human.
Validated Applications
| Target | CD3 |
|---|---|
| Host | Mouse |
| Clonality | Monoclonal |
| Clone | PTR1374 |
| Isotype | IgG1, Kappa |
| Conjugate | Unconjugated |
| Reactivity | Human |
| Applications | Flow Cytometry, ELISA |
| Purification | Affinity Purified |
| Specificity | This recombinant monoclonal antibody can detects endogenous levels of CD3 protein. |
| UniProt / Swiss-Prot | P07766 (Human) |
Recommended dilutions: ELISA 1:5000-100000;Flow Cyt 1-2μg/Test
Immunogen / Antigen
Purified recombinant Human CD3
Reactivity Notes
Confirmed cross-reactivity: Human. Confirm suitability for untested species before use.
Scientific Background
The protein encoded byThis gene is the CD3-epsilon polypeptide, which together with CD3-gamma, -delta and -zeta, and the T-cell receptor alpha/beta and gamma/delta heterodimers, forms the T-cell receptor-CD3 complex.This complex plays an important role in coupling antigen recognition to several intracellular signal-transduction pathways. The genes encoding the epsilon, gamma and delta polypeptides are located in the same cluster on chromosome 11. The epsilon polypeptide plays an essential role in T-cell development. Defects inThis gene cause immunodeficiency.This gene has also been linked to a susceptibility to type I diabetes in women. [provided by RefSeq, Jul 2008]
Safety & Handling
This antibody is validated for Flow Cytometry, ELISA. Recommended dilutions: ELISA 1:5000-100000;Flow Cyt 1-2μg/Test
Confirmed reactivity: Human. Other species should be validated by the user.
Conjugate: Unconjugated.
Store as follows: -15°C to -25°C/1 year(Avoid freeze / thaw cycles)
Clone PTR1374.
Customization & Add-ons: Can't find exactly what you need? Contact us for custom formats, conjugations, bulk quantities, or related products.
