| Field | Specification |
|---|---|
| Target | |
| Antigen | |
| Alternative names | CD4;T-cell surface glycoprotein CD4;T-cell surface antigen T4/Leu-3;CD antigen CD4 |
| Gene ID | |
| Host | |
| Clonality | |
| Reactivity | |
| Applications | |
| Immunogen | Purified recombinant fragment of human CD4 expressed in E. Coli. |
| Conjugate | |
| Purification | |
| Cellular localization | |
| Formulation | |
| Storage | |
| Catalog no. (Mfr.) | |
| Main SKU |
Product Overview
U-Blot® CD4 Mouse Monoclonal Antibody is a mouse monoclonal antibody from UcallM Biosciences Inc, raised against CD4. It has been validated for Flow Cytometry, ELISA and reacts with Human.
Validated Applications
| Target | CD4 |
|---|---|
| Host | Mouse |
| Clonality | Monoclonal |
| Conjugate | Unconjugated |
| Reactivity | Human |
| Applications | Flow Cytometry, ELISA |
| Purification | Affinity Purified |
| Specificity | CD4 Monoclonal Antibody detects endogenous levels of CD4 protein. |
| UniProt / Swiss-Prot | P01730 (Human) | P06332 (Mouse) |
Recommended dilutions: Flow Cyt 1:200-1:400;ELISA 1:10000;Not yet tested in other applications
Immunogen / Antigen
Purified recombinant fragment of human CD4 expressed in E. Coli.
Reactivity Notes
Confirmed cross-reactivity: Human. Confirm suitability for untested species before use.
Scientific Background
This gene encodes a membrane glycoprotein of T lymphocytes that interacts with major histocompatibility complex class II antigenes and is also a receptor for the human immunodeficiency virus. This gene is expressed not only in T lymphocytes, but also in B cells, macrophages, and granulocytes. It is also expressed in specific regions of the brain. The protein functions to initiate or augment the early phase of T-cell activation, and may function as an important mediator of indirect neuronal damage in infectious and immune-mediated diseases of the central nervous system. Multiple alternatively spliced transcript variants encoding different isoforms have been identified in this gene. [provided by RefSeq, Aug 2010]
Safety & Handling
This antibody is validated for Flow Cytometry, ELISA. Recommended dilutions: Flow Cyt 1:200-1:400;ELISA 1:10000;Not yet tested in other applications
Confirmed reactivity: Human. Other species should be validated by the user.
Conjugate: Unconjugated.
Store as follows: -15°C to -25°C/1 year(Do not lower than -25°C)
Customization & Add-ons: Can't find exactly what you need? Contact us for custom formats, conjugations, bulk quantities, or related products.
