| Field | Specification |
|---|---|
| Target | |
| Antigen | |
| Alternative names | ITGA2B;GP2B;ITGAB;Integrin alpha-IIb;GPalpha IIb;GPIIb;Platelet membrane glycoprotein IIb;CD41 |
| Gene ID | |
| Host | |
| Clone | |
| Clonality | |
| Reactivity | |
| Applications | |
| Immunogen | Synthetic Peptide of CD41 |
| Conjugate | |
| Molecular weight | |
| Purification | |
| Cellular localization | |
| Formulation | |
| Storage | |
| Catalog no. (Mfr.) | |
| Main SKU |
Product Overview
U-Blot® CD41 Mouse Monoclonal Antibody (Q90) is a mouse monoclonal antibody from UcallM Biosciences Inc, raised against CD41. It has been validated for Immunohistochemistry, Immunofluorescence and reacts with Human.
Validated Applications
| Target | CD41 |
|---|---|
| Host | Mouse |
| Clonality | Monoclonal |
| Clone | Q90 |
| Conjugate | Unconjugated |
| Reactivity | Human |
| Applications | Immunohistochemistry, Immunofluorescence |
| Purification | Affinity Purified |
| Specificity | The antibody detects endogenous human CD41/ Intergrin α2b protein. |
| Molecular Weight | Calculated: 113 kDa |
| UniProt / Swiss-Prot | P08514 (Human) | Q9QUM0 (Mouse) |
Recommended dilutions: IHC 1:100;IF 1:50-200
Immunogen / Antigen
Synthetic Peptide of CD41
Reactivity Notes
Confirmed cross-reactivity: Human. Confirm suitability for untested species before use.
Scientific Background
This gene encodes a member of the integrin alpha chain family of proteins. The encoded preproprotein is proteolytically processed to generate light and heavy chains that associate through disulfide linkages to form a subunit of the alpha-IIb/beta-3 integrin cell adhesion receptor. This receptor plays a crucial role in the blood coagulation system, by mediating platelet aggregation. Mutations in this gene are associated with platelet-type bleeding disorders, which are characterized by a failure of platelet aggregation, including Glanzmann thrombasthenia. [provided by RefSeq, Jan 2016]
Safety & Handling
This antibody is validated for Immunohistochemistry, Immunofluorescence. Recommended dilutions: IHC 1:100;IF 1:50-200
Confirmed reactivity: Human. Other species should be validated by the user.
Conjugate: Unconjugated.
Store as follows: -15°C to -25°C/1 year(Do not lower than -25°C)
Clone Q90.
Customization & Add-ons: Can't find exactly what you need? Contact us for custom formats, conjugations, bulk quantities, or related products.
