| Field | Specification |
|---|---|
| Target | |
| Antigen | |
| Alternative names | FCAR;CD89;Immunoglobulin alpha Fc receptor ;IgA Fc receptor;CD antigen CD89 |
| Gene ID | |
| Host | |
| Clone | |
| Clonality | |
| Isotype | |
| Reactivity | |
| Applications | |
| Conjugate | |
| Molecular weight | |
| Purification | |
| Cellular localization | |
| Formulation | |
| Storage | |
| Catalog no. (Mfr.) | |
| Main SKU |
Product Overview
U-Blot® CD89 Rabbit Monoclonal Antibody is a rabbit monoclonal antibody from UcallM Biosciences Inc, raised against CD89. It has been validated for Western Blot, Immunohistochemistry, Immunofluorescence, Flow Cytometry, Immunoprecipitation and reacts with Human.
Validated Applications
| Target | CD89 |
|---|---|
| Host | Rabbit |
| Clonality | Monoclonal |
| Clone | PT0770R |
| Isotype | IgG, Kappa |
| Conjugate | Unconjugated |
| Reactivity | Human |
| Applications | Western Blot, Immunohistochemistry, Immunofluorescence, Flow Cytometry, Immunoprecipitation |
| Purification | Protein A |
| Specificity | Endogenous |
| Molecular Weight | Observed: 32 kDa |
| UniProt / Swiss-Prot | P24071 (Human) |
Recommended dilutions: WB 1:1000-5000;IHC 1:100-300;ICC/IF 1:100-300;FC 1:100-300;IP 1:50-100
Immunogen / Antigen
Immunoglobulin alpha Fc receptor;IgA Fc receptor;CD antigen CD89
Reactivity Notes
Confirmed cross-reactivity: Human. Confirm suitability for untested species before use.
Scientific Background
This gene is a member of the immunoglobulin gene superfamily and encodes a receptor for the Fc region of IgA. The receptor is a transmembrane glycoprotein present on the surface of myeloid lineage cells such as neutrophils, monocytes, macrophages, and eosinophils, where it mediates immunologic responses to pathogens. It interacts with IgA-opsonized targets and triggers several immunologic defense processes, including phagocytosis, antibody-dependent cell-mediated cytotoxicity, and stimulation of the release of inflammatory mediators. Multiple alternatively spliced transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, Jul 2008]
Safety & Handling
This antibody is validated for Western Blot, Immunohistochemistry, Immunofluorescence, Flow Cytometry, Immunoprecipitation. Recommended dilutions: WB 1:1000-5000;IHC 1:100-300;ICC/IF 1:100-300;FC 1:100-300;IP 1:50-100
Confirmed reactivity: Human. Other species should be validated by the user.
Conjugate: Unconjugated.
Store as follows: -15°C to -25°C/1 year(Do not lower than -25°C)
Clone PT0770R.
Customization & Add-ons: Can't find exactly what you need? Contact us for custom formats, conjugations, bulk quantities, or related products.
