U-Blot® COPB Rabbit Polyclonal Antibody

SKU:BHA21814480
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    Overview
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    Anti-COPB antibody (Rabbit host, polyclonal, Unconjugated). Validated for Western Blot, ELISA with reactivity to Human, Rat, Mouse.
    Clonality Polyclonal
    Host Rabbit
    Reactivity Human, Rat, Mouse
    Conjugate Unconjugated
    Isotype IgG
    Applications Western Blot, ELISA
    Options selector
    Catalog no. Size
    WP3202-50 50 uL
    WP3202-100 100 uL
    Available Options

    Select the variant that best fits your experiment. Availability and lead time may vary by option.

    • Options: Size: 50 uL
    • Lead time: options listed in "Availability Content"; other statuses may take longer.
    • Storage: -15°C to -25°C/1 year(Do not lower than -25°C)
    • Shipping: cold-chain shipment (typically with ice packs).
    • Upon receipt: store at recommended temperature as soon as possible.
    • Sales terms and conditions: Please review prior to ordering.
    Field Specification
    Antigen
    • Coatomer subunit beta (Beta-coat protein) (Beta-COP)
    Cellular Localization Cytoplasm. Golgi apparatus membrane ; Peripheral membrane protein ; Cytoplasmic side . Cytoplasmic vesicle, COPI-coated vesicle membrane; Peripheral membrane protein ; Cytoplasmic side . Cell membrane . Endoplasmic reticulum-Golgi intermediate compartment . The coatomer is cytoplasmic or polymerized on the cytoplasmic side of the Golgi, as well as on the vesicles/buds originating from it (By similarity). Proteolytic cleavage by CAPN8 triggers translocation from Golgi to cytoplasm (By similarity). Found in perinuclear vesicular-tubular clusters (VTCs) and in the Golgi region where associated with vesicles, buds and rims of the Golgi stack (By similarity). Occasionally present at the trans-side of Golgi, but mainly present at the cis-Golgi side in transitional areas (TA), on so-called peripheral elements (PE) consisting of tubules and vesicles located between the cup-shaped transitional elements (TE) of the rough endoplasmic reticulum (RER) and the cis-most Golgi cisternae (By similarity). Present in cytoplasm, not associated with visible coats or membranes, with a minor fraction present on small clusters of tubules and vesicles (By similarity). Some association with high-density and low-density microsomes and mitochondria/nuclei fraction (By similarity). Very little found in plasma membrane fraction (PubMed:20362547). .
    Clonality
    • Polyclonal
    Concentration 1 mg/ml
    Conjugate
    • Unconjugated
    Formulation PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA
    Gene ID 1315 (Human)
    Host Rabbit
    Immunogen Synthesized peptide derived from part region of human protein AA range: 865-915
    Isotype
    • IgG
    Molecular Weight Observed: 104 kDa
    Product Type
    • Polyclonal Antibody
    • Primary Antibodies
    Reactivity
    • Human
    • Rat
    • Mouse
    Storage -15°C to -25°C/1 year(Do not lower than -25°C)
    Target COPB
    Antibody

    Product Overview

    U-Blot® COPB Rabbit Polyclonal Antibody is a rabbit polyclonal antibody from UcallM Biosciences Inc, raised against COPB. It has been validated for Western Blot, ELISA and reacts with Human, Rat, Mouse.

    Validated Applications

    Target COPB
    Host Rabbit
    Clonality Polyclonal
    Isotype IgG
    Conjugate Unconjugated
    Reactivity Human, Rat, Mouse
    Applications Western Blot, ELISA
    Purification Affinity Purified
    Specificity COPB Polyclonal Antibody detects endogenous levels of protein.
    Molecular Weight Observed: 104 kDa
    UniProt / Swiss-Prot P53618 (Human) | Q9JIF7 (Mouse) | P23514 (Rat)

    Recommended dilutions: WB 1:500-2000;ELISA 1:5000-20000

    Immunogen / Antigen

    Synthesized peptide derived from part region of human protein AA range: 865-915

    Reactivity Notes

    Confirmed cross-reactivity: Human, Rat, Mouse. Confirm suitability for untested species before use.

    Scientific Background

    This gene encodes a protein subunit of the coatomer complex associated with non-clathrin coated vesicles. The coatomer complex, also known as the coat protein complex 1, forms in the cytoplasm and is recruited to the Golgi by activated guanosine triphosphatases. Once at the Golgi membrane, the coatomer complex may assist in the movement of protein and lipid components back to the endoplasmic reticulum. Alternatively spliced transcript variants have been described. [provided by RefSeq, Jan 2009]

    Safety & Handling

    For Research Use Only (RUO). Not for diagnostic or therapeutic use. Store as indicated: -15°C to -25°C/1 year(Do not lower than -25°C)
    What applications is this antibody validated for?

    This antibody is validated for Western Blot, ELISA. Recommended dilutions: WB 1:500-2000;ELISA 1:5000-20000

    What species does it react with?

    Confirmed reactivity: Human, Rat, Mouse. Other species should be validated by the user.

    Is this antibody conjugated?

    Conjugate: Unconjugated.

    How should it be stored?

    Store as follows: -15°C to -25°C/1 year(Do not lower than -25°C)

    Customization & Add-ons: Can't find exactly what you need? Contact us for custom formats, conjugations, bulk quantities, or related products.

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