| Field | Specification |
|---|---|
| Target | |
| Antigen | |
| Alternative names | AL024441;COX 4;COX IV 1;COX IV;COX IV-1;Cox4;COX41_HUMAN;Cox4a;COX4B;COX4I1;COX4I2;COX4L2;COXIV;Cytochrome c oxidase polypeptide IV;Cytochrome c oxidase subunit 4 isoform 1 mitochondrial;Cytochrome c oxidase subunit 4 isoform 1, mitochondrial;Cytochrome C Oxidase subunit IV;Cytochrome c oxidase subunit IV isoform 1;Cytochrome c oxidase subunit IV isoform 2;lung;Cytochrome c oxydase subunit;dJ857M17.2;MGC105470;MGC72016. |
| Gene ID | |
| Host | |
| Clonality | |
| Reactivity | |
| Applications | |
| Immunogen | A synthetic peptide corresponding to carboxyl terminal residues of human COX IV |
| Conjugate | |
| Molecular weight | |
| Purification | |
| Cellular localization | |
| Formulation | |
| Storage | |
| Catalog no. (Mfr.) | |
| Main SKU |
Product Overview
U-Blot® COX IV Mouse Monoclonal Antibody is a mouse monoclonal antibody from UcallM Biosciences Inc, raised against COX IV. It has been validated for Western Blot, Flow Cytometry, Immunofluorescence, Immunoprecipitation, Immunohistochemistry and reacts with Human, Mouse, Rat, Hamster, Goat, Monkey.
Validated Applications
| Target | COX IV |
|---|---|
| Host | Mouse |
| Clonality | Monoclonal |
| Conjugate | Unconjugated |
| Reactivity | Human, Mouse, Rat, Hamster, Goat, Monkey |
| Applications | Western Blot, Flow Cytometry, Immunofluorescence, Immunoprecipitation, Immunohistochemistry |
| Purification | Affinity Purified |
| Specificity | This antibody detects endogenous levels of COX IV and does not cross-react with related proteins. |
| Molecular Weight | Observed: 17 kDa |
| UniProt / Swiss-Prot | P13073 (Human) | P19783 (Mouse) |
Recommended dilutions: WB 1:1000;ICC 1:150;Flow Cyt 1:100
Immunogen / Antigen
A synthetic peptide corresponding to carboxyl terminal residues of human COX IV
Reactivity Notes
Confirmed cross-reactivity: Human, Mouse, Rat, Hamster, Goat, Monkey. Confirm suitability for untested species before use.
Scientific Background
Cytochrome c oxidase (COX) is the terminal enzyme of the mitochondrial respiratory chain. It is a multi-subunit enzyme complex that couples the transfer of electrons from cytochrome c to molecular oxygen and contributes to a proton electrochemical gradient across the inner mitochondrial membrane. The complex consists of 13 mitochondrial- and nuclear-encoded subunits. The mitochondrially-encoded subunits perform the electron transfer and proton pumping activities. The functions of the nuclear-encoded subunits are unknown but they may play a role in the regulation and assembly of the complex. This gene encodes the nuclear-encoded subunit IV isoform 1 of the human mitochondrial respiratory chain enzyme. It is located at the 3' of the NOC4 (neighbor of COX4) gene in a head-to-head orientation, and shares a promoter with it. Pseudogenes related to this gene are located on chromosomes
Safety & Handling
This antibody is validated for Western Blot, Flow Cytometry, Immunofluorescence, Immunoprecipitation, Immunohistochemistry. Recommended dilutions: WB 1:1000;ICC 1:150;Flow Cyt 1:100
Confirmed reactivity: Human, Mouse, Rat, Hamster, Goat, Monkey. Other species should be validated by the user.
Conjugate: Unconjugated.
Store as follows: -15°C to -25°C/1 year(Do not lower than -25°C)
Customization & Add-ons: Can't find exactly what you need? Contact us for custom formats, conjugations, bulk quantities, or related products.
