| Field | Specification |
|---|---|
| Target | |
| Antigen | |
| Alternative names | Carnitine O-palmitoyltransferase 1, liver isoform;CPT1-L;Carnitine O-palmitoyltransferase I, liver isoform;CPT I;CPTI-L;Carnitine palmitoyltransferase 1A |
| Gene ID | |
| Host | |
| Clonality | |
| Isotype | |
| Reactivity | |
| Applications | |
| Immunogen | Synthesized peptide derived from human CPT1A. AA range 40-80 |
| Conjugate | |
| Molecular weight | |
| Purification | |
| Cellular localization | |
| Concentration | |
| Formulation | |
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| Catalog no. (Mfr.) | |
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Product Overview
U-Blot® CPT1A Rabbit Polyclonal Antibody is a rabbit polyclonal antibody from UcallM Biosciences Inc, raised against CPT1A. It has been validated for Western Blot and reacts with Human, Mouse, Rat, Dog.
Validated Applications
| Target | CPT1A |
|---|---|
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugate | Unconjugated |
| Reactivity | Human, Mouse, Rat, Dog |
| Applications | Western Blot |
| Purification | Affinity Purified |
| Specificity | This antibody detects endogenous levels of CPT1A at Human/Mouse/Rat |
| Molecular Weight | Observed: 85 kDa |
| UniProt / Swiss-Prot | P50416 (Human) | P97742 (Mouse) | P32198 (Rat) |
Recommended dilutions: WB 1:500-2000
Immunogen / Antigen
Synthesized peptide derived from human CPT1A. AA range 40-80
Reactivity Notes
Confirmed cross-reactivity: Human, Mouse, Rat, Dog. Confirm suitability for untested species before use.
Scientific Background
The mitochondrial oxidation of long-chain fatty acids is initiated by the sequential action of carnitine palmitoyltransferase I (which is located in the outer membrane and is detergent-labile) and carnitine palmitoyltransferase II (which is located in the inner membrane and is detergent-stable), together with a carnitine-acylcarnitine translocase. CPT I is the key enzyme in the carnitine-dependent transport across the mitochondrial inner membrane and its deficiency results in a decreased rate of fatty acid beta-oxidation. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
Safety & Handling
This antibody is validated for Western Blot. Recommended dilutions: WB 1:500-2000
Confirmed reactivity: Human, Mouse, Rat, Dog. Other species should be validated by the user.
Conjugate: Unconjugated.
Store as follows: -15°C to -25°C/1 year(Do not lower than -25°C)
Customization & Add-ons: Can't find exactly what you need? Contact us for custom formats, conjugations, bulk quantities, or related products.
