| Field | Specification |
|---|---|
| Target | |
| Antigen | |
| Alternative names | Cyclophilin B |
| Gene ID | |
| Host | |
| Clone | |
| Clonality | |
| Isotype | |
| Reactivity | |
| Applications | |
| Conjugate | |
| Purification | |
| Cellular localization | |
| Concentration | |
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| Catalog no. (Mfr.) | |
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Product Overview
U-Blot® Cyclophilin B Mouse Monoclonal Antibody (2B10), AbFluor 647 Conjugated is a mouse monoclonal antibody from UcallM Biosciences Inc, raised against Cyclophilin B. It has been validated for Immunofluorescence, Western Blot, Immunohistochemistry and reacts with Human, Rat, Mouse.
Validated Applications
| Target | Cyclophilin B |
|---|---|
| Host | Mouse |
| Clonality | Monoclonal |
| Clone | 2B10 |
| Isotype | IgG |
| Conjugate | AbFluor 647 |
| Reactivity | Human, Rat, Mouse |
| Applications | Immunofluorescence, Western Blot, Immunohistochemistry |
| Purification | Affinity Purified |
| Specificity | Cyclophilin B Monoclonal Antibody(2B10) AbFluor™ 647 Conjugated specially designed for your Immunofluorescence analysis. |
| UniProt / Swiss-Prot | P23284 (Human) |
Recommended dilutions: Optimal working dilutions should be determined experimentally by the investigator;Suggested starting dilutions are as follows:IHC 1:50-300;IF 1:50-200.
Immunogen / Antigen
Peptidyl-prolyl cis-trans isomerase B (PPIase B) (CYP-S1) (Cyclophilin B) (Rotamase B) (S-cyclophilin) (SCYLP)
Reactivity Notes
Confirmed cross-reactivity: Human, Rat, Mouse. Confirm suitability for untested species before use.
Scientific Background
The protein encoded by this gene is a cyclosporine-binding protein and is mainly located within the endoplasmic reticulum. It is associated with the secretory pathway and released in biological fluids. This protein can bind to cells derived from T- and B-lymphocytes, and may regulate cyclosporine A-mediated immunosuppression. Variants have been identified in this protein that give rise to recessive forms of osteogenesis imperfecta. [provided by RefSeq, Oct 2009]
Safety & Handling
This antibody is validated for Immunofluorescence, Western Blot, Immunohistochemistry. Recommended dilutions: Optimal working dilutions should be determined experimentally by the investigator;Suggested starting dilutions are as follows:IHC 1:50-300;IF 1:50-200.
Confirmed reactivity: Human, Rat, Mouse. Other species should be validated by the user.
Conjugate: AbFluor 647.
Store as follows: Stable for one year at -15°C to -25°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing. Store in dark.
Clone 2B10.
Customization & Add-ons: Can't find exactly what you need? Contact us for custom formats, conjugations, bulk quantities, or related products.
