| Field | Specification |
|---|---|
| Target | |
| Antigen | |
| Alternative names | PPIB;CYPB;Peptidyl-prolyl cis-trans isomerase B;PPIase B;CYP-S1;Cyclophilin B;Rotamase B;S-cyclophilin;SCYLP |
| Gene ID | |
| Host | |
| Clone | |
| Clonality | |
| Reactivity | |
| Applications | |
| Immunogen | Synthetic Peptide of Cyclophilin B |
| Conjugate | |
| Molecular weight | |
| Purification | |
| Cellular localization | |
| Concentration | |
| Formulation | |
| Storage | |
| Catalog no. (Mfr.) | |
| Main SKU |
Product Overview
U-Blot® Cyclophilin B Mouse Monoclonal Antibody (2B10) is a mouse monoclonal antibody from UcallM Biosciences Inc, raised against Cyclophilin B. It has been validated for Immunofluorescence, Western Blot, Immunohistochemistry and reacts with Human, Rat, Mouse.
Validated Applications
| Target | Cyclophilin B |
|---|---|
| Host | Mouse |
| Clonality | Monoclonal |
| Clone | 2B10 |
| Conjugate | Unconjugated |
| Reactivity | Human, Rat, Mouse |
| Applications | Immunofluorescence, Western Blot, Immunohistochemistry |
| Purification | Affinity Purified |
| Specificity | Cyclophilin B protein detects endogenous levels of Cyclophilin B |
| Molecular Weight | Observed: 21 kDa |
| UniProt / Swiss-Prot | P23284 (Human) | P24369 (Mouse) | P24368 (Rat) |
Recommended dilutions: IF 1:50-200;WB 1:1000-2000;IHC 1:50-300
Immunogen / Antigen
Synthetic Peptide of Cyclophilin B
Reactivity Notes
Confirmed cross-reactivity: Human, Rat, Mouse. Confirm suitability for untested species before use.
Scientific Background
The protein encoded by this gene is a cyclosporine-binding protein and is mainly located within the endoplasmic reticulum. It is associated with the secretory pathway and released in biological fluids. This protein can bind to cells derived from T- and B-lymphocytes, and may regulate cyclosporine A-mediated immunosuppression. Variants have been identified in this protein that give rise to recessive forms of osteogenesis imperfecta. [provided by RefSeq, Oct 2009]
Safety & Handling
This antibody is validated for Immunofluorescence, Western Blot, Immunohistochemistry. Recommended dilutions: IF 1:50-200;WB 1:1000-2000;IHC 1:50-300
Confirmed reactivity: Human, Rat, Mouse. Other species should be validated by the user.
Conjugate: Unconjugated.
Store as follows: -15°C to -25°C/1 year(Do not lower than -25°C)
Clone 2B10.
Customization & Add-ons: Can't find exactly what you need? Contact us for custom formats, conjugations, bulk quantities, or related products.
