| Field | Specification |
|---|---|
| Target | |
| Antigen | |
| Alternative names | Keratin, type I cytoskeletal 14;Cytokeratin-14;CK-14;Keratin-14;K14 |
| Gene ID | |
| Host | |
| Clone | |
| Clonality | |
| Isotype | |
| Reactivity | |
| Applications | |
| Immunogen | Synthesized peptide derived from human CK14 AA range: 400-472 |
| Conjugate | |
| Molecular weight | |
| Purification | |
| Cellular localization | |
| Formulation | |
| Storage | |
| Catalog no. (Mfr.) | |
| Main SKU |
Product Overview
U-Blot® Cytokeratin 14 (ABT047) Mouse Monoclonal Antibody (WM1598) is a mouse monoclonal antibody from UcallM Biosciences Inc, raised against Cytokeratin 14. It has been validated for Immunohistochemistry, ELISA and reacts with Human, Mouse, Rat.
Validated Applications
| Target | Cytokeratin 14 |
|---|---|
| Host | Mouse |
| Clonality | Monoclonal |
| Clone | ABT047 |
| Isotype | IgG2b, Kappa |
| Conjugate | Unconjugated |
| Reactivity | Human, Mouse, Rat |
| Applications | Immunohistochemistry, ELISA |
| Purification | Affinity Purified |
| Specificity | The antibody can specifically recognize human CK14 protein. In immunohistochemistry on formalin-fixed, paraffin-embedded tissue sections, the antibody specifically labels the basal cell of squamous epithelial cells and glandular epithelia, myoepithelium and mesothelial cells. |
| Molecular Weight | Calculated: 52 kDa | Observed: 53 kDa |
| UniProt / Swiss-Prot | P02533 (Human) |
Recommended dilutions: IHC 1:200-400;ELISA 1:500-5000
Immunogen / Antigen
Synthesized peptide derived from human CK14 AA range: 400-472
Reactivity Notes
Confirmed cross-reactivity: Human, Mouse, Rat. Confirm suitability for untested species before use.
Scientific Background
This gene encodes a member of the keratin family, the most diverse group of intermediate filaments. This gene product, a type I keratin, is usually found as a heterotetramer with two keratin 5 molecules, a type II keratin. Together they form the cytoskeleton of epithelial cells. Mutations in the genes for these keratins are associated with epidermolysis bullosa simplex. At least one pseudogene has been identified at 17p12-p11. [provided by RefSeq, Jul 2008]
Safety & Handling
This antibody is validated for Immunohistochemistry, ELISA. Recommended dilutions: IHC 1:200-400;ELISA 1:500-5000
Confirmed reactivity: Human, Mouse, Rat. Other species should be validated by the user.
Conjugate: Unconjugated.
Store as follows: -15°C to -25°C/1 year(Do not lower than -25°C)
Clone ABT047.
Customization & Add-ons: Can't find exactly what you need? Contact us for custom formats, conjugations, bulk quantities, or related products.
