| Field | Specification |
|---|---|
| Target | |
| Antigen | |
| Alternative names | Keratin, type I cytoskeletal 16;Cytokeratin-16;CK-16;Keratin-16;K16 |
| Gene ID | |
| Host | |
| Clone | |
| Clonality | |
| Isotype | |
| Reactivity | |
| Applications | |
| Immunogen | Synthesized peptide derived from human CK16 AA range: 400-473 |
| Conjugate | |
| Molecular weight | |
| Purification | |
| Cellular localization | |
| Formulation | |
| Storage | |
| Catalog no. (Mfr.) | |
| Main SKU |
Product Overview
U-Blot® Cytokeratin 16 (ABT059) Mouse Monoclonal Antibody (WM1701) is a mouse monoclonal antibody from UcallM Biosciences Inc, raised against Cytokeratin 16. It has been validated for Immunohistochemistry, ELISA and reacts with Human.
Validated Applications
| Target | Cytokeratin 16 |
|---|---|
| Host | Mouse |
| Clonality | Monoclonal |
| Clone | ABT059 |
| Isotype | IgG2b, Kappa |
| Conjugate | Unconjugated |
| Reactivity | Human |
| Applications | Immunohistochemistry, ELISA |
| Purification | Affinity Purified |
| Specificity | The antibody can specifically recognize human CK16 protein, and shows no cross reaction with CK1, 5, 6, 7, 8, 10, 13, 14, 15, 19, 20. |
| Molecular Weight | Calculated: 51 kDa | Observed: 55 kDa |
| UniProt / Swiss-Prot | P08779 (Human) |
Recommended dilutions: IHC 1:200-400;ELISA 1:500-5000
Immunogen / Antigen
Synthesized peptide derived from human CK16 AA range: 400-473
Reactivity Notes
Confirmed cross-reactivity: Human. Confirm suitability for untested species before use.
Scientific Background
The protein encoded by this gene is a member of the keratin gene family. The keratins are intermediate filament proteins responsible for the structural integrity of epithelial cells and are subdivided into cytokeratins and hair keratins. Most of the type I cytokeratins consist of acidic proteins which are arranged in pairs of heterotypic keratin chains and are clustered in a region of chromosome 17q12-q21. This keratin has been coexpressed with keratin 14 in a number of epithelial tissues, including esophagus, tongue, and hair follicles. Mutations in this gene are associated with type 1 pachyonychia congenita, non-epidermolytic palmoplantar keratoderma and unilateral palmoplantar verrucous nevus. [provided by RefSeq, Jul 2008]
Safety & Handling
This antibody is validated for Immunohistochemistry, ELISA. Recommended dilutions: IHC 1:200-400;ELISA 1:500-5000
Confirmed reactivity: Human. Other species should be validated by the user.
Conjugate: Unconjugated.
Store as follows: -15°C to -25°C/1 year(Do not lower than -25°C)
Clone ABT059.
Customization & Add-ons: Can't find exactly what you need? Contact us for custom formats, conjugations, bulk quantities, or related products.
