| Field | Specification |
|---|---|
| Target | |
| Antigen | |
| Alternative names | Keratin, type I cytoskeletal 19;Cytokeratin-19;CK-19;Keratin-19;K19 |
| Gene ID | |
| Host | |
| Clone | |
| Clonality | |
| Isotype | |
| Reactivity | |
| Applications | |
| Immunogen | Recombinant protein |
| Conjugate | |
| Molecular weight | |
| Purification | |
| Cellular localization | |
| Formulation | |
| Storage | |
| Catalog no. (Mfr.) | |
| Main SKU |
Product Overview
U-Blot® Cytokeratin 19 (ABT010) Mouse Monoclonal Antibody (WM1545) is a mouse monoclonal antibody from UcallM Biosciences Inc, raised against Cytokeratin 19. It has been validated for Immunohistochemistry, Western Blot, Immunofluorescence, ELISA and reacts with Human.
Validated Applications
| Target | Cytokeratin 19 |
|---|---|
| Host | Mouse |
| Clonality | Monoclonal |
| Clone | ABT010 |
| Isotype | IgG1, Kappa |
| Conjugate | Unconjugated |
| Reactivity | Human |
| Applications | Immunohistochemistry, Western Blot, Immunofluorescence, ELISA |
| Purification | Protein G |
| Specificity | This antibody detects endogenous levels of Cytokeratin 19 protein. |
| Molecular Weight | Calculated: 44 kDa | Observed: 44 kDa |
| UniProt / Swiss-Prot | P08727 (Human) |
Recommended dilutions: IHC 1:200-1000;WB 1:500-2000.IF 1:100-500.ELISA 1:1000-5000.
Immunogen / Antigen
Recombinant protein
Reactivity Notes
Confirmed cross-reactivity: Human. Confirm suitability for untested species before use.
Scientific Background
The protein encoded by this gene is a member of the keratin family. The keratins are intermediate filament proteins responsible for the structural integrity of epithelial cells and are subdivided into cytokeratins and hair keratins. The type I cytokeratins consist of acidic proteins which are arranged in pairs of heterotypic keratin chains. Unlike its related family members, this smallest known acidic cytokeratin is not paired with a basic cytokeratin in epithelial cells. It is specifically expressed in the periderm, the transiently superficial layer that envelopes the developing epidermis. The type I cytokeratins are clustered in a region of chromosome 17q12-q21. [provided by RefSeq, Jul 2008]
Safety & Handling
This antibody is validated for Immunohistochemistry, Western Blot, Immunofluorescence, ELISA. Recommended dilutions: IHC 1:200-1000;WB 1:500-2000.IF 1:100-500.ELISA 1:1000-5000.
Confirmed reactivity: Human. Other species should be validated by the user.
Conjugate: Unconjugated.
Store as follows: -15°C to -25°C/1 year(Do not lower than -25°C)
Clone ABT010.
Customization & Add-ons: Can't find exactly what you need? Contact us for custom formats, conjugations, bulk quantities, or related products.