| Field | Specification |
|---|---|
| Target | |
| Alternative names | DNA dependent protein kinase catalytic subuni;DNA PKcs;DNA-dependent protein kinase catalytic subunit;DNA-PK catalytic subunit;DNAPK;DNPK1;hyper radiosensitivity of murine scid mutation, complementing 1;HYRC;HYRC1;p350;p460;PRKDC;PRKDC_HUMAN;protein kinase, DNA activated, catalytic polypeptide;XRCC7. |
| Gene ID | |
| Host | |
| Clonality | |
| Reactivity | |
| Applications | |
| Immunogen | Purified recombinant human DNA-PKcs protein fragments expressed in E.coli |
| Conjugate | |
| Molecular weight | |
| Purification | |
| Cellular localization | |
| Formulation | |
| Storage | |
| Catalog no. (Mfr.) | |
| Main SKU |
Product Overview
U-Blot® DNA-PKcs Mouse Monoclonal Antibody is a mouse monoclonal antibody from UcallM Biosciences Inc, raised against DNA-PKcs. It has been validated for Western Blot, Immunoprecipitation, Immunofluorescence, Immunohistochemistry and reacts with Human.
Validated Applications
| Target | DNA-PKcs |
|---|---|
| Host | Mouse |
| Clonality | Monoclonal |
| Conjugate | Unconjugated |
| Reactivity | Human |
| Applications | Western Blot, Immunoprecipitation, Immunofluorescence, Immunohistochemistry |
| Purification | Affinity Purified |
| Specificity | This antibody detects endogenous levels of DNA-PKcs and does not cross-react with related proteins. |
| Molecular Weight | Observed: 450 kDa |
| UniProt / Swiss-Prot | P78527 (Human) | P97313 (Mouse) |
Recommended dilutions: WB 1:1000;ICC 1:100
Immunogen / Antigen
Purified recombinant human DNA-PKcs protein fragments expressed in E.coli
Reactivity Notes
Confirmed cross-reactivity: Human. Confirm suitability for untested species before use.
Scientific Background
This gene encodes the catalytic subunit of the DNA-dependent protein kinase (DNA-PK). It functions with the Ku70/Ku80 heterodimer protein in DNA double strand break repair and recombination. The protein encoded is a member of the PI3/PI4-kinase family.[provided by RefSeq, Jul 2010]
Safety & Handling
This antibody is validated for Western Blot, Immunoprecipitation, Immunofluorescence, Immunohistochemistry. Recommended dilutions: WB 1:1000;ICC 1:100
Confirmed reactivity: Human. Other species should be validated by the user.
Conjugate: Unconjugated.
Store as follows: -15°C to -25°C/1 year(Do not lower than -25°C)
Customization & Add-ons: Can't find exactly what you need? Contact us for custom formats, conjugations, bulk quantities, or related products.
