| Field | Specification |
|---|---|
| Mfr No | |
| Alternative Names | Epidermal growth factor receptor;Proto-oncogene c-ErbB-1;Receptor tyrosine-protein kinase erbB-1 |
| Antigen | |
| Cellular Localization | |
| Clonality | |
| Concentration | |
| Conjugate | |
| Formulation | |
| Gene ID | |
| Host | |
| Immunogen | Synthesized peptide derived from human EGFR (Phospho-Tyr998) |
| Isotype | |
| Molecular Weight | |
| Product Type | |
| Reactivity | |
| Storage | |
| Target |
Product Overview
U-Blot® EGFR (Phospho Tyr998) Rabbit Polyclonal Antibody is a rabbit polyclonal antibody from UcallM Biosciences Inc, raised against EGFR. Recognizes Phospho. It has been validated for Immunohistochemistry, Immunofluorescence, Western Blot and reacts with Human, Mouse, Rat.
Validated Applications
| Target | EGFR |
|---|---|
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugate | Unconjugated |
| Reactivity | Human, Mouse, Rat |
| Applications | Immunohistochemistry, Immunofluorescence, Western Blot |
| Purification | Affinity Purified |
| Specificity | This antibody detects endogenous phospho levels of EGFR (Phospho-Tyr998) at Human:Y998, Mouse:Y1000, Rat:Y999 |
| Molecular Weight | Observed: 175 kDa |
| UniProt / Swiss-Prot | P00533 (Human) |
Recommended dilutions: IHC 1:50-200;WB 1:500-2000;IF 1:50-200
Immunogen / Antigen
Synthesized peptide derived from human EGFR (Phospho-Tyr998)
Reactivity Notes
Confirmed cross-reactivity: Human, Mouse, Rat. Confirm suitability for untested species before use.
Scientific Background
The protein encoded by this gene is a transmembrane glycoprotein that is a member of the protein kinase superfamily. This protein is a receptor for members of the epidermal growth factor family. EGFR is a cell surface protein that binds to epidermal growth factor. Binding of the protein to a ligand induces receptor dimerization and tyrosine autophosphorylation and leads to cell proliferation. Mutations in this gene are associated with lung cancer. [provided by RefSeq, Jun 2016]
Safety & Handling
This antibody is validated for Immunohistochemistry, Immunofluorescence, Western Blot. Recommended dilutions: IHC 1:50-200;WB 1:500-2000;IF 1:50-200
Confirmed reactivity: Human, Mouse, Rat. Other species should be validated by the user.
Conjugate: Unconjugated.
Store as follows: -15°C to -25°C/1 year(Do not lower than -25°C)
Customization & Add-ons: Can't find exactly what you need? Contact us for custom formats, conjugations, bulk quantities, or related products.
