U-Blot® EphA2 (Phospho Tyr772) Rabbit Polyclonal Antibody

SKU:BHA21804726
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UcallM Biosciences Inc
UcallM Biosciences Inc
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Overview
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Anti-EphA2 antibody (Rabbit host, polyclonal, Unconjugated). Validated for Western Blot with reactivity to Human, Rat, Mouse.
Clonality Polyclonal
Host Rabbit
Reactivity Human, Rat, Mouse
Conjugate Unconjugated
Isotype IgG
Applications Western Blot
Options selector
Catalog no. Size
WP10351-50 50 uL
WP10351-100 100 uL
Available Options

Select the variant that best fits your experiment. Availability and lead time may vary by option.

  • Options: Size: 50 uL
  • Lead time: options listed in "Availability Content"; other statuses may take longer.
  • Storage: -15°C to -25°C/1 year(Do not lower than -25°C)
  • Shipping: cold-chain shipment (typically with ice packs).
  • Upon receipt: store at recommended temperature as soon as possible.
  • Sales terms and conditions: Please review prior to ordering.
Field Specification
Target EphA2
Antigen
  • EphA2 (Tyr772)
Alternative names Ephrin type-A receptor 2;Epithelial cell kinase;Tyrosine-protein kinase receptor ECK
Gene ID 1969 (Human) | 13836 (Mouse)
Host Rabbit
Clonality
  • Polyclonal
Isotype
  • IgG
Reactivity
  • Human
  • Rat
  • Mouse
Applications
  • Western Blot
Immunogen Synthesized phosho peptide around human EphA2 (Tyr772)
Conjugate
  • Unconjugated
Molecular weight Observed: 105 kDa
Purification Affinity Purified
Cellular localization Cell membrane ; Single-pass type I membrane protein . Cell projection, ruffle membrane ; Single-pass type I membrane protein . Cell projection, lamellipodium membrane ; Single-pass type I membrane protein . Cell junction, focal adhesion . Present at regions of cell-cell contacts but also at the leading edge of migrating cells (PubMed:19573808, PubMed:20861311). Relocates from the plasma membrane to the cytoplasmic and perinuclear regions in cancer cells (PubMed:18794797). .
Concentration 1 mg/ml
Formulation Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Storage -15°C to -25°C/1 year(Do not lower than -25°C)
Catalog no. (Mfr.) WP10351
Main SKU BHA21804726
Antibody

Product Overview

U-Blot® EphA2 (Phospho Tyr772) Rabbit Polyclonal Antibody is a rabbit polyclonal antibody from UcallM Biosciences Inc, raised against EphA2. Recognizes Phospho. It has been validated for Western Blot and reacts with Human, Rat, Mouse.

Validated Applications

Target EphA2
Host Rabbit
Clonality Polyclonal
Isotype IgG
Conjugate Unconjugated
Reactivity Human, Rat, Mouse
Applications Western Blot
Purification Affinity Purified
Specificity This antibody detects endogenous levels of Human EphA2 (phospho-Tyr772)
Molecular Weight Observed: 105 kDa
UniProt / Swiss-Prot P29317 (Human) | Q03145 (Mouse)

Recommended dilutions: WB 1:1000-2000

Immunogen / Antigen

Synthesized phosho peptide around human EphA2 (Tyr772)

Reactivity Notes

Confirmed cross-reactivity: Human, Rat, Mouse. Confirm suitability for untested species before use.

Scientific Background

This gene belongs to the ephrin receptor subfamily of the protein-tyrosine kinase family. EPH and EPH-related receptors have been implicated in mediating developmental events, particularly in the nervous system. Receptors in the EPH subfamily typically have a single kinase domain and an extracellular region containing a Cys-rich domain and 2 fibronectin type III repeats. The ephrin receptors are divided into 2 groups based on the similarity of their extracellular domain sequences and their affinities for binding ephrin-A and ephrin-B ligands. This gene encodes a protein that binds ephrin-A ligands. Mutations in this gene are the cause of certain genetically-related cataract disorders.[provided by RefSeq, May 2010]

Safety & Handling

For Research Use Only (RUO). Not for diagnostic or therapeutic use. Store as indicated: -15°C to -25°C/1 year(Do not lower than -25°C)
What applications is this antibody validated for?

This antibody is validated for Western Blot. Recommended dilutions: WB 1:1000-2000

What species does it react with?

Confirmed reactivity: Human, Rat, Mouse. Other species should be validated by the user.

Is this antibody conjugated?

Conjugate: Unconjugated.

How should it be stored?

Store as follows: -15°C to -25°C/1 year(Do not lower than -25°C)

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