| Field | Specification |
|---|---|
| Target | |
| Alternative names | [Acyl-carrier-protein] S acetyltransferase;[Acyl-carrier-protein] S malonyltransferase;3-hydroxypalmitoyl-[acyl-carrier-protein] dehydratase;3-oxoacyl-[acyl-carrier-protein] reductase;3-oxoacyl-[acyl-carrier-protein] synthase;Enoyl-[acyl-carrier-protein] |
| Gene ID | |
| Host | |
| Clonality | |
| Reactivity | |
| Applications | |
| Immunogen | Purified recombinant human Fatty Acid Synthase protein fragments expressed in E.coli. |
| Conjugate | |
| Molecular weight | |
| Purification | |
| Cellular localization | |
| Formulation | |
| Storage | |
| Catalog no. (Mfr.) | |
| Main SKU |
Product Overview
U-Blot® Fatty Acid Synthase Mouse Monoclonal Antibody is a mouse monoclonal antibody from UcallM Biosciences Inc, raised against Fatty Acid Synthase. It has been validated for Western Blot, Immunoprecipitation, Immunofluorescence and reacts with Human, Mouse, Rat, Monkey, Bovine.
Validated Applications
| Target | Fatty Acid Synthase |
|---|---|
| Host | Mouse |
| Clonality | Monoclonal |
| Conjugate | Unconjugated |
| Reactivity | Human, Mouse, Rat, Monkey, Bovine |
| Applications | Western Blot, Immunoprecipitation, Immunofluorescence |
| Purification | Affinity Purified |
| Specificity | This antibody detects endogenous levels of Fatty Acid Synthase and does not cross-react with related proteins. |
| Molecular Weight | Observed: 273 kDa |
| UniProt / Swiss-Prot | P49327 (Human) | P19096 (Mouse) |
Recommended dilutions: WB 1:1000;ICC 1:400;IF 1:50-200
Immunogen / Antigen
Purified recombinant human Fatty Acid Synthase protein fragments expressed in E.coli.
Reactivity Notes
Confirmed cross-reactivity: Human, Mouse, Rat, Monkey, Bovine. Confirm suitability for untested species before use.
Scientific Background
The enzyme encoded by this gene is a multifunctional protein. Its main function is to catalyze the synthesis of palmitate from acetyl-CoA and malonyl-CoA, in the presence of NADPH, into long-chain saturated fatty acids. In some cancer cell lines, this protein has been found to be fused with estrogen receptor-alpha (ER-alpha), in which the N-terminus of FAS is fused in-frame with the C-terminus of ER-alpha. [provided by RefSeq, Jul 2008]
Safety & Handling
This antibody is validated for Western Blot, Immunoprecipitation, Immunofluorescence. Recommended dilutions: WB 1:1000;ICC 1:400;IF 1:50-200
Confirmed reactivity: Human, Mouse, Rat, Monkey, Bovine. Other species should be validated by the user.
Conjugate: Unconjugated.
Store as follows: -15°C to -25°C/1 year(Do not lower than -25°C)
Customization & Add-ons: Can't find exactly what you need? Contact us for custom formats, conjugations, bulk quantities, or related products.
