| Field | Specification |
|---|---|
| Target | |
| Antigen | |
| Alternative names | Fibroblast growth factor receptor 3;FGFR-3;CD antigen CD333 |
| Gene ID | |
| Host | |
| Clonality | |
| Reactivity | |
| Applications | |
| Immunogen | Synthesized peptide derived from human FGFR3 (Phospho Tyr577) |
| Conjugate | |
| Molecular weight | |
| Purification | |
| Cellular localization | |
| Concentration | |
| Formulation | |
| Storage | |
| Catalog no. (Mfr.) | |
| Main SKU |
Product Overview
U-Blot® FGFR3 (Phospho Tyr577) Rabbit Polyclonal Antibody is a rabbit polyclonal antibody from UcallM Biosciences Inc, raised against FGFR3. Recognizes Phospho. It has been validated for Immunohistochemistry, Western Blot and reacts with Human, Mouse.
Validated Applications
| Target | FGFR3 |
|---|---|
| Host | Rabbit |
| Clonality | Polyclonal |
| Conjugate | Unconjugated |
| Reactivity | Human, Mouse |
| Applications | Immunohistochemistry, Western Blot |
| Purification | Affinity Purified |
| Specificity | This antibody detects endogenous levels of FGFR3 (Phospho Tyr577) Rabbit pAb at Human, Mouse |
| Molecular Weight | Observed: 95 kDa |
| UniProt / Swiss-Prot | P22607 (Human) | Q61851 (Mouse) |
Recommended dilutions: WB 1:500-2000;IHC 1:50-200
Immunogen / Antigen
Synthesized peptide derived from human FGFR3 (Phospho Tyr577)
Reactivity Notes
Confirmed cross-reactivity: Human, Mouse. Confirm suitability for untested species before use.
Scientific Background
fibroblast growth factor receptor 3(FGFR3) Homo sapiens This gene encodes a member of the fibroblast growth factor receptor (FGFR) family, with its amino acid sequence being highly conserved between members and among divergent species. FGFR family members differ from one another in their ligand affinities and tissue distribution. A full-length representative protein would consist of an extracellular region, composed of three immunoglobulin-like domains, a single hydrophobic membrane-spanning segment and a cytoplasmic tyrosine kinase domain. The extracellular portion of the protein interacts with fibroblast growth factors, setting in motion a cascade of downstream signals, ultimately influencing mitogenesis and differentiation. This particular family member binds acidic and basic fibroblast growth hormone and plays a role in bone development and maintenance. Mutations in this gene lead to craniosynostosis and multiple types of skeletal dys
Safety & Handling
This antibody is validated for Immunohistochemistry, Western Blot. Recommended dilutions: WB 1:500-2000;IHC 1:50-200
Confirmed reactivity: Human, Mouse. Other species should be validated by the user.
Conjugate: Unconjugated.
Store as follows: -15°C to -25°C/1 year(Do not lower than -25°C)
Customization & Add-ons: Can't find exactly what you need? Contact us for custom formats, conjugations, bulk quantities, or related products.
