| Field | Specification |
|---|---|
| Target | |
| Antigen | |
| Alternative names | FZD4;Frizzled-4;Fz-4;hFz4;FzE4;CD antigen CD344 |
| Gene ID | |
| Host | |
| Clonality | |
| Isotype | |
| Reactivity | |
| Applications | |
| Immunogen | The antiserum was produced against synthesized peptide derived from human FZD4. AA range:131-180 |
| Conjugate | |
| Molecular weight | |
| Purification | |
| Cellular localization | |
| Concentration | |
| Formulation | |
| Storage | |
| Catalog no. (Mfr.) | |
| Main SKU |
Product Overview
U-Blot® Frizzled-4 Rabbit Polyclonal Antibody (WP12364) is a rabbit polyclonal antibody from UcallM Biosciences Inc, raised against Frizzled-4. It has been validated for Immunofluorescence, ELISA and reacts with Human, Mouse, Rat.
Validated Applications
| Target | Frizzled-4 |
|---|---|
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugate | Unconjugated |
| Reactivity | Human, Mouse, Rat |
| Applications | Immunofluorescence, ELISA |
| Purification | Affinity Purified |
| Specificity | Frizzled-4 Polyclonal Antibody detects endogenous levels of Frizzled-4 protein. |
| Molecular Weight | Calculated: 60 kDa |
| UniProt / Swiss-Prot | Q9ULV1 (Human) | Q61088 (Mouse) | Q9QZH0 (Rat) |
Recommended dilutions: IF 1:200-1:1000;ELISA 1:5000;Not yet tested in other applications
Immunogen / Antigen
The antiserum was produced against synthesized peptide derived from human FZD4. AA range:131-180
Reactivity Notes
Confirmed cross-reactivity: Human, Mouse, Rat. Confirm suitability for untested species before use.
Scientific Background
frizzled class receptor 4(FZD4) Homo sapiens This gene is a member of the frizzled gene family. Members of this family encode seven-transmembrane domain proteins that are receptors for the Wingless type MMTV integration site family of signaling proteins. Most frizzled receptors are coupled to the beta-catenin canonical signaling pathway. This protein may play a role as a positive regulator of the Wingless type MMTV integration site signaling pathway. A transcript variant retaining intronic sequence and encoding a shorter isoform has been described, however, its expression is not supported by other experimental evidence. [provided by RefSeq, Jul 2008]
Safety & Handling
This antibody is validated for Immunofluorescence, ELISA. Recommended dilutions: IF 1:200-1:1000;ELISA 1:5000;Not yet tested in other applications
Confirmed reactivity: Human, Mouse, Rat. Other species should be validated by the user.
Conjugate: Unconjugated.
Store as follows: -15°C to -25°C/1 year(Do not lower than -25°C)
Customization & Add-ons: Can't find exactly what you need? Contact us for custom formats, conjugations, bulk quantities, or related products.
