| Field | Specification |
|---|---|
| Target | |
| Antigen | |
| Alternative names | FZD7;Frizzled-7;Fz-7;hFz7;FzE3 |
| Gene ID | |
| Host | |
| Clonality | |
| Isotype | |
| Reactivity | |
| Applications | |
| Immunogen | The antiserum was produced against synthesized peptide derived from human FZD7. AA range:45-94 |
| Conjugate | |
| Molecular weight | |
| Purification | |
| Cellular localization | |
| Concentration | |
| Formulation | |
| Storage | |
| Catalog no. (Mfr.) | |
| Main SKU |
Product Overview
U-Blot® Frizzled-7 Rabbit Polyclonal Antibody is a rabbit polyclonal antibody from UcallM Biosciences Inc, raised against Frizzled-7. It has been validated for Western Blot, Flow Cytometry, Immunofluorescence, ELISA and reacts with Human, Mouse.
Validated Applications
| Target | Frizzled-7 |
|---|---|
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugate | Unconjugated |
| Reactivity | Human, Mouse |
| Applications | Western Blot, Flow Cytometry, Immunofluorescence, ELISA |
| Purification | Affinity Purified |
| Specificity | Frizzled-7 Polyclonal Antibody detects endogenous levels of Frizzled-7 protein. |
| Molecular Weight | Observed: 64 kDa |
| UniProt / Swiss-Prot | O75084 (Human) | Q61090 (Mouse) |
Recommended dilutions: WB 1:500-2000;Flow Cyt 1:50-200;IF/ICC1:100-500;ELISA 1:5000-20000
Immunogen / Antigen
The antiserum was produced against synthesized peptide derived from human FZD7. AA range:45-94
Reactivity Notes
Confirmed cross-reactivity: Human, Mouse. Confirm suitability for untested species before use.
Scientific Background
frizzled class receptor 7(FZD7) Homo sapiens Members of the 'frizzled' gene family encode 7-transmembrane domain proteins that are receptors for Wnt signaling proteins. The FZD7 protein contains an N-terminal signal sequence, 10 cysteine residues typical of the cysteine-rich extracellular domain of Fz family members, 7 putative transmembrane domains, and an intracellular C-terminal tail with a PDZ domain-binding motif. FZD7 gene expression may downregulate APC function and enhance beta-catenin-mediated signals in poorly differentiated human esophageal carcinomas. [provided by RefSeq, Jul 2008]
Safety & Handling
This antibody is validated for Western Blot, Flow Cytometry, Immunofluorescence, ELISA. Recommended dilutions: WB 1:500-2000;Flow Cyt 1:50-200;IF/ICC1:100-500;ELISA 1:5000-20000
Confirmed reactivity: Human, Mouse. Other species should be validated by the user.
Conjugate: Unconjugated.
Store as follows: -15°C to -25°C/1 year(Do not lower than -25°C)
Customization & Add-ons: Can't find exactly what you need? Contact us for custom formats, conjugations, bulk quantities, or related products.
