| Field | Specification |
|---|---|
| Target | |
| Antigen | |
| Alternative names | Ras GTPase-activating protein-binding protein 1;G3BP-1;EC 3.6.4.13;ATP-dependent DNA helicase VIII;hDH VIII;GAP SH3 domain-binding protein 1 |
| Gene ID | |
| Host | |
| Clonality | |
| Reactivity | |
| Applications | |
| Immunogen | Synthesized peptide derived from human G3BP-1 (Phospho Ser149) |
| Conjugate | |
| Molecular weight | |
| Purification | |
| Cellular localization | |
| Concentration | |
| Formulation | |
| Storage | |
| Catalog no. (Mfr.) | |
| Main SKU |
Product Overview
U-Blot® G3BP-1 (Phospho Ser149) Rabbit Polyclonal Antibody is a rabbit polyclonal antibody from UcallM Biosciences Inc, raised against G3BP1. Recognizes Phospho. It has been validated for Immunohistochemistry, Western Blot and reacts with Human, Mouse.
Validated Applications
| Target | G3BP1 |
|---|---|
| Host | Rabbit |
| Clonality | Polyclonal |
| Conjugate | Unconjugated |
| Reactivity | Human, Mouse |
| Applications | Immunohistochemistry, Western Blot |
| Purification | Affinity Purified |
| Specificity | This antibody detects endogenous levels of G3BP-1 (Phospho Ser149) Rabbit pAb at Human, Mouse |
| Molecular Weight | Observed: 52 60 kDa |
| UniProt / Swiss-Prot | Q13283 (Human) | P97855 (Mouse) |
Recommended dilutions: WB 1:500-2000;IHC 1:50-200
Immunogen / Antigen
Synthesized peptide derived from human G3BP-1 (Phospho Ser149)
Reactivity Notes
Confirmed cross-reactivity: Human, Mouse. Confirm suitability for untested species before use.
Scientific Background
G3BP stress granule assembly factor 1(G3BP1) Homo sapiens This gene encodes one of the DNA-unwinding enzymes which prefers partially unwound 3'-tailed substrates and can also unwind partial RNA/DNA and RNA/RNA duplexes in an ATP-dependent fashion. This enzyme is a member of the heterogeneous nuclear RNA-binding proteins and is also an element of the Ras signal transduction pathway. It binds specifically to the Ras-GTPase-activating protein by associating with its SH3 domain. Several alternatively spliced transcript variants of this gene have been described, but the full-length nature of some of these variants has not been determined. [provided by RefSeq, Jul 2008]
Safety & Handling
This antibody is validated for Immunohistochemistry, Western Blot. Recommended dilutions: WB 1:500-2000;IHC 1:50-200
Confirmed reactivity: Human, Mouse. Other species should be validated by the user.
Conjugate: Unconjugated.
Store as follows: -15°C to -25°C/1 year(Do not lower than -25°C)
Customization & Add-ons: Can't find exactly what you need? Contact us for custom formats, conjugations, bulk quantities, or related products.
