| Field | Specification |
|---|---|
| Target | |
| Antigen | |
| Alternative names | Glial fibrillary acidic protein;GFAP |
| Gene ID | |
| Host | |
| Clone | |
| Clonality | |
| Isotype | |
| Reactivity | |
| Applications | |
| Immunogen | Synthesized peptide derived from human GFAP AA range: 300-432 |
| Conjugate | |
| Molecular weight | |
| Purification | |
| Cellular localization | |
| Formulation | |
| Storage | |
| Catalog no. (Mfr.) | |
| Main SKU |
Product Overview
U-Blot® Glial Fibrillary Acidic Protein (GFAP) (ABT176) Mouse Monoclonal Antibody (WM1708) is a mouse monoclonal antibody from UcallM Biosciences Inc, raised against GFAP. It has been validated for Immunohistochemistry, ELISA and reacts with Human, Rat, Monkey, Bovine.
Validated Applications
| Target | GFAP |
|---|---|
| Host | Mouse |
| Clonality | Monoclonal |
| Clone | ABT176 |
| Isotype | IgG2b, Kappa |
| Conjugate | Unconjugated |
| Reactivity | Human, Rat, Monkey, Bovine |
| Applications | Immunohistochemistry, ELISA |
| Purification | Affinity Purified |
| Specificity | The antibody can specifically recognize human GFAP protein. |
| Molecular Weight | Calculated: 49 kDa | Observed: 50 kDa |
| UniProt / Swiss-Prot | P14136 (Human) |
Recommended dilutions: IHC 1:200-400;ELISA 1:500-5000
Immunogen / Antigen
Synthesized peptide derived from human GFAP AA range: 300-432
Reactivity Notes
Confirmed cross-reactivity: Human, Rat, Monkey, Bovine. Confirm suitability for untested species before use.
Scientific Background
This gene encodes one of the major intermediate filament proteins of mature astrocytes. It is used as a marker to distinguish astrocytes from other glial cells during development. Mutations in this gene cause Alexander disease, a rare disorder of astrocytes in the central nervous system. Alternative splicing results in multiple transcript variants encoding distinct isoforms. [provided by RefSeq, Oct 2008]
Safety & Handling
This antibody is validated for Immunohistochemistry, ELISA. Recommended dilutions: IHC 1:200-400;ELISA 1:500-5000
Confirmed reactivity: Human, Rat, Monkey, Bovine. Other species should be validated by the user.
Conjugate: Unconjugated.
Store as follows: -15°C to -25°C/1 year(Do not lower than -25°C)
Clone ABT176.
Customization & Add-ons: Can't find exactly what you need? Contact us for custom formats, conjugations, bulk quantities, or related products.
