| Field | Specification |
|---|---|
| Target | |
| Antigen | |
| Alternative names | GLYT2 NET1 |
| Gene ID | |
| Host | |
| Clone | |
| Clonality | |
| Isotype | |
| Reactivity | |
| Applications | |
| Conjugate | |
| Molecular weight | |
| Purification | |
| Cellular localization | |
| Formulation | |
| Storage | |
| Catalog no. (Mfr.) | |
| Main SKU |
Product Overview
U-Blot® Glyt2 Rabbit Monoclonal Antibody is a rabbit monoclonal antibody from UcallM Biosciences Inc, raised against Glyt2. It has been validated for Western Blot and reacts with Human, Mouse, Rat.
Validated Applications
| Target | Glyt2 |
|---|---|
| Host | Rabbit |
| Clonality | Monoclonal |
| Clone | PT1132R |
| Isotype | IgG, Kappa |
| Conjugate | Unconjugated |
| Reactivity | Human, Mouse, Rat |
| Applications | Western Blot |
| Purification | Protein A |
| Specificity | Endogenous |
| Molecular Weight | Calculated: 88 kDa | Observed: 88 kDa |
| UniProt / Swiss-Prot | Q9Y345 (Human) | Q761V0 (Mouse) | P58295 (Rat) |
Recommended dilutions: WB 1:1000-1:5000
Immunogen / Antigen
Sodium- and chloride-dependent glycine transporter 2 (GlyT-2) (GlyT2) (Solute carrier family 6 member 5)
Reactivity Notes
Confirmed cross-reactivity: Human, Mouse, Rat. Confirm suitability for untested species before use.
Scientific Background
This gene encodes a sodium- and chloride-dependent glycine neurotransmitter transporter. This integral membrane glycoprotein is responsible for the clearance of extracellular glycine during glycine-mediated neurotransmission. This protein is found in glycinergic axons and maintains a high presynaptic pool of neurotransmitter at glycinergic synapses. Mutations in this gene cause hyperekplexia; a heterogenous neurological disorder characterized by exaggerated startle responses and neonatal apnea. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jan 2016]
Safety & Handling
This antibody is validated for Western Blot. Recommended dilutions: WB 1:1000-1:5000
Confirmed reactivity: Human, Mouse, Rat. Other species should be validated by the user.
Conjugate: Unconjugated.
Store as follows: -15°C to -25°C/1 year(Do not lower than -25°C)
Clone PT1132R.
Customization & Add-ons: Can't find exactly what you need? Contact us for custom formats, conjugations, bulk quantities, or related products.
