U-Blot® GPR143 Rabbit Polyclonal Antibody

SKU:BHA21807126
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UcallM Biosciences Inc
UcallM Biosciences Inc
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Overview
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Anti-GPR143 antibody (Rabbit host, polyclonal, Unconjugated). Validated for Immunofluorescence, ELISA with reactivity to Human, Mouse.
Clonality Polyclonal
Host Rabbit
Reactivity Human, Mouse
Conjugate Unconjugated
Isotype IgG
Applications Immunofluorescence, ELISA
Options selector
Catalog no. Size
WP12534-50 50 uL
WP12534-100 100 uL
Available Options

Select the variant that best fits your experiment. Availability and lead time may vary by option.

  • Options: Size: 50 uL
  • Lead time: options listed in "Availability Content"; other statuses may take longer.
  • Storage: -15°C to -25°C/1 year(Do not lower than -25°C)
  • Shipping: cold-chain shipment (typically with ice packs).
  • Upon receipt: store at recommended temperature as soon as possible.
  • Sales terms and conditions: Please review prior to ordering.
Field Specification
Target GPR143
Antigen
  • G-protein coupled receptor 143
Alternative names GPR143;OA1;G-protein coupled receptor 143;Ocular albinism type 1 protein
Gene ID 4935 (Human) | 18241 (Mouse)
Host Rabbit
Clonality
  • Polyclonal
Isotype
  • IgG
Reactivity
  • Human
  • Mouse
Applications
  • Immunofluorescence
  • ELISA
Immunogen The antiserum was produced against synthesized peptide derived from human GPR143. AA range:151-200
Conjugate
  • Unconjugated
Molecular weight Calculated: 44 kDa
Purification Affinity Purified
Cellular localization Melanosome membrane ; Multi-pass membrane protein . Lysosome membrane ; Multi-pass membrane protein . Apical cell membrane ; Multi-pass membrane protein . Distributed throughout the endo-melanosomal system but most of endogenous protein is localized in unpigmented stage II melanosomes. Its expression on the apical cell membrane is sensitive to tyrosine (PubMed:18828673). .
Concentration 1 mg/ml
Formulation Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Storage -15°C to -25°C/1 year(Do not lower than -25°C)
Catalog no. (Mfr.) WP12534
Main SKU BHA21807126
Antibody

Product Overview

U-Blot® GPR143 Rabbit Polyclonal Antibody is a rabbit polyclonal antibody from UcallM Biosciences Inc, raised against GPR143. It has been validated for Immunofluorescence, ELISA and reacts with Human, Mouse.

Validated Applications

Target GPR143
Host Rabbit
Clonality Polyclonal
Isotype IgG
Conjugate Unconjugated
Reactivity Human, Mouse
Applications Immunofluorescence, ELISA
Purification Affinity Purified
Specificity GPR143 Polyclonal Antibody detects endogenous levels of GPR143 protein.
Molecular Weight Calculated: 44 kDa
UniProt / Swiss-Prot P51810 (Human) | P70259 (Mouse)

Recommended dilutions: IF 1:200-1:1000;ELISA 1:10000;Not yet tested in other applications

Immunogen / Antigen

The antiserum was produced against synthesized peptide derived from human GPR143. AA range:151-200

Reactivity Notes

Confirmed cross-reactivity: Human, Mouse. Confirm suitability for untested species before use.

Scientific Background

This gene encodes a protein that binds to heterotrimeric G proteins and is targeted to melanosomes in pigment cells. This protein is thought to be involved in intracellular signal transduction mechanisms. Mutations in this gene cause ocular albinism type 1, also referred to as Nettleship-Falls type ocular albinism, a severe visual disorder. A related pseudogene has been identified on chromosome Y. [provided by RefSeq, Dec 2009]

Safety & Handling

For Research Use Only (RUO). Not for diagnostic or therapeutic use. Store as indicated: -15°C to -25°C/1 year(Do not lower than -25°C)
What applications is this antibody validated for?

This antibody is validated for Immunofluorescence, ELISA. Recommended dilutions: IF 1:200-1:1000;ELISA 1:10000;Not yet tested in other applications

What species does it react with?

Confirmed reactivity: Human, Mouse. Other species should be validated by the user.

Is this antibody conjugated?

Conjugate: Unconjugated.

How should it be stored?

Store as follows: -15°C to -25°C/1 year(Do not lower than -25°C)

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