| Field | Specification |
|---|---|
| Target | |
| Antigen | |
| Alternative names | Glutamate receptor, ionotropic kainate 2;Excitatory amino acid receptor 4;EAA4;Glutamate receptor 6;GluR-6;GluR6 |
| Gene ID | |
| Host | |
| Clonality | |
| Isotype | |
| Reactivity | |
| Applications | |
| Immunogen | Synthetic Peptide of GRIK2 (GluR6) AA range: 119-169 |
| Conjugate | |
| Molecular weight | |
| Purification | |
| Cellular localization | |
| Concentration | |
| Formulation | |
| Storage | |
| Catalog no. (Mfr.) | |
| Main SKU |
Product Overview
U-Blot® GRIK2 (GluR6) Rabbit Polyclonal Antibody is a rabbit polyclonal antibody from UcallM Biosciences Inc, raised against GRIK2. It has been validated for Immunohistochemistry, Immunofluorescence and reacts with Human.
Validated Applications
| Target | GRIK2 |
|---|---|
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugate | Unconjugated |
| Reactivity | Human |
| Applications | Immunohistochemistry, Immunofluorescence |
| Purification | Affinity Purified |
| Specificity | GRIK2(GluR6) protein(A240) detects endogenous levels of GRIK2(GluR6) |
| Molecular Weight | Observed: 103 kDa |
| UniProt / Swiss-Prot | Q13002 (Human) | P39087 (Mouse) |
Recommended dilutions: IHC 1:100-200;IF 1:50-200
Immunogen / Antigen
Synthetic Peptide of GRIK2 (GluR6) AA range: 119-169
Reactivity Notes
Confirmed cross-reactivity: Human. Confirm suitability for untested species before use.
Scientific Background
Glutamate receptors are the predominant excitatory neurotransmitter receptors in the mammalian brain and are activated in a variety of normal neurophysiologic processes. This gene product belongs to the kainate family of glutamate receptors, which are composed of four subunits and function as ligand-activated ion channels. The subunit encoded by this gene is subject to RNA editing at multiple sites within the first and second transmembrane domains, which is thought to alter the structure and function of the receptor complex. Alternatively spliced transcript variants encoding different isoforms have also been described for this gene. Mutations in this gene have been associated with autosomal recessive mental retardation. [provided by RefSeq, Jul 2008]
Safety & Handling
This antibody is validated for Immunohistochemistry, Immunofluorescence. Recommended dilutions: IHC 1:100-200;IF 1:50-200
Confirmed reactivity: Human. Other species should be validated by the user.
Conjugate: Unconjugated.
Store as follows: -15°C to -25°C/1 year(Do not lower than -25°C)
Customization & Add-ons: Can't find exactly what you need? Contact us for custom formats, conjugations, bulk quantities, or related products.
