| Field | Specification |
|---|---|
| Target | |
| Antigen | |
| Alternative names | GSK3B;Glycogen synthase kinase-3 beta;GSK-3 beta;Serine/threonine-protein kinase GSK3B |
| Gene ID | |
| Host | |
| Clonality | |
| Isotype | |
| Reactivity | |
| Applications | |
| Immunogen | The antiserum was produced against synthesized peptide derived from human GSK3 beta around the phosphorylation site of Ser9. AA range:1-50 |
| Conjugate | |
| Molecular weight | |
| Purification | |
| Cellular localization | |
| Concentration | |
| Formulation | |
| Storage | |
| Catalog no. (Mfr.) | |
| Main SKU |
Product Overview
U-Blot® GSK3β (Phospho Ser9) Rabbit Polyclonal Antibody (WP9157) is a rabbit polyclonal antibody from UcallM Biosciences Inc, raised against GSK3β. Recognizes Phospho. It has been validated for Immunofluorescence, Western Blot, Immunohistochemistry, Immunoprecipitation, ELISA and reacts with Human, Mouse, Rat, Drosophila.
Validated Applications
| Target | GSK3β |
|---|---|
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugate | Unconjugated |
| Reactivity | Human, Mouse, Rat, Drosophila |
| Applications | Immunofluorescence, Western Blot, Immunohistochemistry, Immunoprecipitation, ELISA |
| Purification | Affinity Purified |
| Specificity | Phospho-GSK3β (S9) Polyclonal Antibody detects endogenous levels of GSK3β protein only when phosphorylated at S9. |
| Molecular Weight | Observed: 48 kDa |
| UniProt / Swiss-Prot | P49841 (Human) | Q9WV60 (Mouse) | P18266 (Rat) |
Recommended dilutions: IF 1:50-200;WB 1:500-1:2000;IHC 1:100-1:300;IP 2-5 ug:mg lysate;ELISA 1:5000;Not yet tested in other applications
Immunogen / Antigen
The antiserum was produced against synthesized peptide derived from human GSK3 beta around the phosphorylation site of Ser9. AA range:1-50
Reactivity Notes
Confirmed cross-reactivity: Human, Mouse, Rat, Drosophila. Confirm suitability for untested species before use.
Scientific Background
The protein encoded by this gene is a serine-threonine kinase, belonging to the glycogen synthase kinase subfamily. It is involved in energy metabolism, neuronal cell development, and body pattern formation. Polymorphisms in this gene have been implicated in modifying risk of Parkinson disease, and studies in mice show that overexpression of this gene may be relevant to the pathogenesis of Alzheimer disease. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Sep 2009]
Safety & Handling
This antibody is validated for Immunofluorescence, Western Blot, Immunohistochemistry, Immunoprecipitation, ELISA. Recommended dilutions: IF 1:50-200;WB 1:500-1:2000;IHC 1:100-1:300;IP 2-5 ug:mg lysate;ELISA 1:5000;Not yet tested in other applications
Confirmed reactivity: Human, Mouse, Rat, Drosophila. Other species should be validated by the user.
Conjugate: Unconjugated.
Store as follows: -15°C to -25°C/1 year(Do not lower than -25°C)
Customization & Add-ons: Can't find exactly what you need? Contact us for custom formats, conjugations, bulk quantities, or related products.
