| Field | Specification |
|---|---|
| Target | |
| Alternative names | Deubiquitinating enzyme 7;HAUSP;herpes virus associated;Herpes virus associated ubiquitin specific protease;Herpesvirus-associated ubiquitin-specific protease;TEF 1;tef-1;TEF1;Ubiquitin carboxyl terminal hydrolase 7;Ubiquitin carboxyl-terminal hydrolase 7;Ubiquitin specific peptidase 7;herpes virus associated;Ubiquitin specific peptidase 7;Ubiquitin specific peptidase 7 herpes virus associated;Ubiquitin specific processing protease 7;Ubiquitin specific protease 7;herpes virus associated;Ubiquitin Specific Protease 7;Ubiquitin specific protease 7 herpes virus associated;Ubiquitin thioesterase 7;ubiquitin thiolesterase 7;Ubiquitin-specific-processing protease 7;UBP 7;UBP-7;UBP7;UBP7_HUMAN;USP 7;usp-7;USP7;VMW110-ASSOCIATED PROTEIN,135-KD. |
| Gene ID | |
| Host | |
| Clonality | |
| Reactivity | |
| Applications | |
| Immunogen | Purified recombinant human HAUSP / USP7 protein fragments expressed in E.coli. |
| Conjugate | |
| Molecular weight | |
| Purification | |
| Cellular localization | |
| Formulation | |
| Storage | |
| Catalog no. (Mfr.) | |
| Main SKU |
Product Overview
U-Blot® HAUSP/USP7 Mouse Monoclonal Antibody is a mouse monoclonal antibody from UcallM Biosciences Inc, raised against HAUSP/USP7. It has been validated for Western Blot and reacts with Human.
Validated Applications
| Target | HAUSP/USP7 |
|---|---|
| Host | Mouse |
| Clonality | Monoclonal |
| Conjugate | Unconjugated |
| Reactivity | Human |
| Applications | Western Blot |
| Purification | Affinity Purified |
| Specificity | This antibody detects endogenous levels of HAUSP / USP7 and does not cross-react with related proteins. |
| Molecular Weight | Observed: 135 kDa |
| UniProt / Swiss-Prot | Q93009 (Human) | Q6A4J8 (Mouse) |
Recommended dilutions: WB 1:200
Immunogen / Antigen
Purified recombinant human HAUSP / USP7 protein fragments expressed in E.coli.
Reactivity Notes
Confirmed cross-reactivity: Human. Confirm suitability for untested species before use.
Scientific Background
The protein encoded by this gene belongs to the peptidase C19 family, which includes ubiquitinyl hydrolases. This protein deubiquitinates target proteins such as p53 (a tumor suppressor protein) and WASH (essential for endosomal protein recycling), and regulates their activities by counteracting the opposing ubiquitin ligase activity of proteins such as HDM2 and TRIM27, involved in the respective process. Mutations in this gene have been implicated in a neurodevelopmental disorder. [provided by RefSeq, Mar 2016]
Safety & Handling
This antibody is validated for Western Blot. Recommended dilutions: WB 1:200
Confirmed reactivity: Human. Other species should be validated by the user.
Conjugate: Unconjugated.
Store as follows: -15°C to -25°C/1 year(Do not lower than -25°C)
Customization & Add-ons: Can't find exactly what you need? Contact us for custom formats, conjugations, bulk quantities, or related products.
