| Field | Specification |
|---|---|
| Target | |
| Alternative names | DKFZp686M1669;Hexokinase 2;Hexokinase 2 muscle;Hexokinase type II;Hexokinase-2;HK 2;HK II;HK2;HKII;HxK 2;HxK2;HXK2_HUMAN;Muscle form hexokinase. |
| Gene ID | |
| Host | |
| Clonality | |
| Reactivity | |
| Applications | |
| Immunogen | Recombinant human Hexokinase II protein. |
| Conjugate | |
| Molecular weight | |
| Purification | |
| Cellular localization | |
| Formulation | |
| Storage | |
| Catalog no. (Mfr.) | |
| Main SKU |
Product Overview
U-Blot® Hexokinase II Mouse Monoclonal Antibody is a mouse monoclonal antibody from UcallM Biosciences Inc, raised against HXK II. It has been validated for Western Blot and reacts with Rat, Mouse, Monkey.
Validated Applications
| Target | HXK II |
|---|---|
| Host | Mouse |
| Clonality | Monoclonal |
| Conjugate | Unconjugated |
| Reactivity | Rat, Mouse, Monkey |
| Applications | Western Blot |
| Purification | Affinity Purified |
| Specificity | This antibody detects endogenous levels of Hexokinase II and does not cross-react with related proteins. |
| Molecular Weight | Observed: 102 kDa |
| UniProt / Swiss-Prot | P52789 (Human) | O08528 (Mouse) |
Recommended dilutions: WB 1:500
Immunogen / Antigen
Recombinant human Hexokinase II protein.
Reactivity Notes
Confirmed cross-reactivity: Rat, Mouse, Monkey. Confirm suitability for untested species before use.
Scientific Background
Hexokinases phosphorylate glucose to produce glucose-6-phosphate, the first step in most glucose metabolism pathways. This gene encodes hexokinase 2, the predominant form found in skeletal muscle. It localizes to the outer membrane of mitochondria. Expression of this gene is insulin-responsive, and studies in rat suggest that it is involved in the increased rate of glycolysis seen in rapidly growing cancer cells. [provided by RefSeq, Apr 2009]
Safety & Handling
This antibody is validated for Western Blot. Recommended dilutions: WB 1:500
Confirmed reactivity: Rat, Mouse, Monkey. Other species should be validated by the user.
Conjugate: Unconjugated.
Store as follows: -15°C to -25°C/1 year(Do not lower than -25°C)
Customization & Add-ons: Can't find exactly what you need? Contact us for custom formats, conjugations, bulk quantities, or related products.
