U-Blot® HSC70 Mouse Monoclonal Antibody (7G12)

SKU:BHA21802653
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UcallM Biosciences Inc
UcallM Biosciences Inc
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Overview
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Anti-HSC70 antibody (Mouse host, monoclonal, Unconjugated). Validated for Immunohistochemistry, Western Blot with reactivity to Human, Mouse, Rat.
Clonality Monoclonal
Host Mouse
Reactivity Human, Mouse, Rat
Conjugate Unconjugated
Clone 7G12
Applications Immunohistochemistry, Western Blot
Options selector
Catalog no. Size
WM1096-50 50 uL
WM1096-100 100 uL
Available Options

Select the variant that best fits your experiment. Availability and lead time may vary by option.

  • Options: Size: 50 uL
  • Lead time: options listed in "Availability Content"; other statuses may take longer.
  • Storage: -15°C to -25°C/1 year(Do not lower than -25°C)
  • Shipping: cold-chain shipment (typically with ice packs).
  • Upon receipt: store at recommended temperature as soon as possible.
  • Sales terms and conditions: Please review prior to ordering.
Field Specification
Target HSC70
Antigen
  • HSC70
Alternative names Heat shock cognate 71 kDa protein;Heat shock 70 kDa protein 8
Gene ID 3312 (Human) | 15481 (Mouse) | 24468 (Rat)
Host Mouse
Clone 7G12
Clonality
  • Monoclonal
Reactivity
  • Human
  • Mouse
  • Rat
Applications
  • Immunohistochemistry
  • Western Blot
Immunogen Synthesized peptide derived from human HSC70
Conjugate
  • Unconjugated
Molecular weight Observed: 73 kDa
Purification Affinity Purified
Cellular localization Cytoplasm. Melanosome. Nucleus, nucleolus. Cell membrane. Localized in cytoplasmic mRNP granules containing untranslated mRNAs. Translocates rapidly from the cytoplasm to the nuclei, and especially to the nucleoli, upon heat shock.
Concentration 1 mg/ml
Formulation Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Storage -15°C to -25°C/1 year(Do not lower than -25°C)
Catalog no. (Mfr.) WM1096
Main SKU BHA21802653
Antibody

Product Overview

U-Blot® HSC70 Mouse Monoclonal Antibody (7G12) is a mouse monoclonal antibody from UcallM Biosciences Inc, raised against HSC70. It has been validated for Immunohistochemistry, Western Blot and reacts with Human, Mouse, Rat.

Validated Applications

Target HSC70
Host Mouse
Clonality Monoclonal
Clone 7G12
Conjugate Unconjugated
Reactivity Human, Mouse, Rat
Applications Immunohistochemistry, Western Blot
Purification Affinity Purified
Specificity This antibody detects endogenous levels of HSC70 at Human, Mouse,Rat
Molecular Weight Observed: 73 kDa
UniProt / Swiss-Prot P11142 (Human) | P63017 (Mouse) | P63018 (Rat)

Recommended dilutions: IHC1:50-200;WB 1:1000-2000

Immunogen / Antigen

Synthesized peptide derived from human HSC70

Reactivity Notes

Confirmed cross-reactivity: Human, Mouse, Rat. Confirm suitability for untested species before use.

Scientific Background

This gene encodes a member of the heat shock protein 70 family, which contains both heat-inducible and constitutively expressed members. This protein belongs to the latter group, which are also referred to as heat-shock cognate proteins. It functions as a chaperone, and binds to nascent polypeptides to facilitate correct folding. It also functions as an ATPase in the disassembly of clathrin-coated vesicles during transport of membrane components through the cell. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Aug 2011]

Safety & Handling

For Research Use Only (RUO). Not for diagnostic or therapeutic use. Store as indicated: -15°C to -25°C/1 year(Do not lower than -25°C)
What applications is this antibody validated for?

This antibody is validated for Immunohistochemistry, Western Blot. Recommended dilutions: IHC1:50-200;WB 1:1000-2000

What species does it react with?

Confirmed reactivity: Human, Mouse, Rat. Other species should be validated by the user.

Is this antibody conjugated?

Conjugate: Unconjugated.

How should it be stored?

Store as follows: -15°C to -25°C/1 year(Do not lower than -25°C)

What is the clone number?

Clone 7G12.

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