| Field | Specification |
|---|---|
| Target | |
| Antigen | |
| Alternative names | 60 kDa heat shock protein, mitochondrial;60 kDa chaperonin;Chaperonin 60;CPN60;Heat shock protein 60;HSP-60;Hsp60;HuCHA60;Mitochondrial matrix protein P1;P60 lymphocyte protein |
| Gene ID | |
| Host | |
| Clone | |
| Clonality | |
| Isotype | |
| Reactivity | |
| Applications | |
| Immunogen | Synthesized peptide derived from human HSP60 AA range: 500-573 |
| Conjugate | |
| Molecular weight | |
| Purification | |
| Cellular localization | |
| Formulation | |
| Storage | |
| Catalog no. (Mfr.) | |
| Main SKU |
Product Overview
U-Blot® HSP60 (ABT186) Mouse Monoclonal Antibody (WM1713) is a mouse monoclonal antibody from UcallM Biosciences Inc, raised against HSP60. It has been validated for Immunohistochemistry, ELISA and reacts with Human, Mouse, Rat.
Validated Applications
| Target | HSP60 |
|---|---|
| Host | Mouse |
| Clonality | Monoclonal |
| Clone | ABT186 |
| Isotype | IgG2b, Kappa |
| Conjugate | Unconjugated |
| Reactivity | Human, Mouse, Rat |
| Applications | Immunohistochemistry, ELISA |
| Purification | Affinity Purified |
| Specificity | The antibody can specifically recognize human HSP60 protein. |
| Molecular Weight | Calculated: 60 kDa | Observed: 60 kDa |
| UniProt / Swiss-Prot | P10809 (Human) |
Recommended dilutions: IHC 1:200-400;ELISA 1:500-5000
Immunogen / Antigen
Synthesized peptide derived from human HSP60 AA range: 500-573
Reactivity Notes
Confirmed cross-reactivity: Human, Mouse, Rat. Confirm suitability for untested species before use.
Scientific Background
This gene encodes a member of the chaperonin family. The encoded mitochondrial protein may function as a signaling molecule in the innate immune system. This protein is essential for the folding and assembly of newly imported proteins in the mitochondria. This gene is adjacent to a related family member and the region between the 2 genes functions as a bidirectional promoter. Several pseudogenes have been associated with this gene. Two transcript variants encoding the same protein have been identified for this gene. Mutations associated with this gene cause autosomal recessive spastic paraplegia 13. [provided by RefSeq, Jun 2010]
Safety & Handling
This antibody is validated for Immunohistochemistry, ELISA. Recommended dilutions: IHC 1:200-400;ELISA 1:500-5000
Confirmed reactivity: Human, Mouse, Rat. Other species should be validated by the user.
Conjugate: Unconjugated.
Store as follows: -15°C to -25°C/1 year(Do not lower than -25°C)
Clone ABT186.
Customization & Add-ons: Can't find exactly what you need? Contact us for custom formats, conjugations, bulk quantities, or related products.
