| Field | Specification |
|---|---|
| Target | |
| Antigen | |
| Alternative names | HSPB8;CRYAC;E2IG1;HSP22;PP1629;Heat shock protein beta-8;HspB8;Alpha-crystallin C chain;E2-induced gene 1 protein;Protein kinase H11;Small stress protein-like protein HSP22 |
| Gene ID | |
| Host | |
| Clone | |
| Clonality | |
| Reactivity | |
| Applications | |
| Immunogen | Recombinant Protein of HSPB8/HSP22 |
| Conjugate | |
| Molecular weight | |
| Purification | |
| Cellular localization | |
| Concentration | |
| Formulation | |
| Storage | |
| Catalog no. (Mfr.) | |
| Main SKU |
Product Overview
U-Blot® HSPB8/HSP22 Mouse Monoclonal Antibody (2C3) is a mouse monoclonal antibody from UcallM Biosciences Inc, raised against HSPB8. It has been validated for Western Blot and reacts with Human, Rat, Mouse.
Validated Applications
| Target | HSPB8 |
|---|---|
| Host | Mouse |
| Clonality | Monoclonal |
| Clone | 2C3 |
| Conjugate | Unconjugated |
| Reactivity | Human, Rat, Mouse |
| Applications | Western Blot |
| Purification | Affinity Purified |
| Specificity | HSPB8/HSP22 protein detects endogenous levels of HSPB8/HSP22 |
| Molecular Weight | Observed: 22 kDa |
| UniProt / Swiss-Prot | Q9UJY1 (Human) | Q9JK92 (Mouse) | Q9EPX0 (Rat) |
Recommended dilutions: WB 1:1000-2000
Immunogen / Antigen
Recombinant Protein of HSPB8/HSP22
Reactivity Notes
Confirmed cross-reactivity: Human, Rat, Mouse. Confirm suitability for untested species before use.
Scientific Background
The protein encoded by this gene belongs to the superfamily of small heat-shock proteins containing a conservative alpha-crystallin domain at the C-terminal part of the molecule. The expression of this gene in induced by estrogen in estrogen receptor-positive breast cancer cells, and this protein also functions as a chaperone in association with Bag3, a stimulator of macroautophagy. Thus, this gene appears to be involved in regulation of cell proliferation, apoptosis, and carcinogenesis, and mutations in this gene have been associated with different neuromuscular diseases, including Charcot-Marie-Tooth disease. [provided by RefSeq, Jul 2008]
Safety & Handling
This antibody is validated for Western Blot. Recommended dilutions: WB 1:1000-2000
Confirmed reactivity: Human, Rat, Mouse. Other species should be validated by the user.
Conjugate: Unconjugated.
Store as follows: -15°C to -25°C/1 year(Do not lower than -25°C)
Clone 2C3.
Customization & Add-ons: Can't find exactly what you need? Contact us for custom formats, conjugations, bulk quantities, or related products.
