| Field | Specification |
|---|---|
| Target | |
| Alternative names | High temperature requirement protein A2;HTRA 2;HtrA like serine protease;HtrA serine peptidase 2;HtrA, E. coli, homolog of, 2;HtrA2;HTRA2_HUMAN;mitochondrial;Omi stress regulated endoprotease;Omi stress-regulated endoprotease;PARK 13;PARK13;Protease serin |
| Gene ID | |
| Host | |
| Clonality | |
| Reactivity | |
| Applications | |
| Immunogen | Recombinant human HtrA2/Omi protein. |
| Conjugate | |
| Molecular weight | |
| Purification | |
| Cellular localization | |
| Formulation | |
| Storage | |
| Catalog no. (Mfr.) | |
| Main SKU |
Product Overview
U-Blot® HtrA2 Mouse Monoclonal Antibody is a mouse monoclonal antibody from UcallM Biosciences Inc, raised against HtrA2. It has been validated for Western Blot and reacts with Human.
Validated Applications
| Target | HtrA2 |
|---|---|
| Host | Mouse |
| Clonality | Monoclonal |
| Conjugate | Unconjugated |
| Reactivity | Human |
| Applications | Western Blot |
| Purification | Affinity Purified |
| Specificity | This antibody detects endogenous levels of HtrA2/Omi and does not cross-react with related proteins. |
| Molecular Weight | Calculated: 49 kDa |
| UniProt / Swiss-Prot | O43464 (Human) | Q9JIY5 (Mouse) |
Recommended dilutions: WB 1:500
Immunogen / Antigen
Recombinant human HtrA2/Omi protein.
Reactivity Notes
Confirmed cross-reactivity: Human. Confirm suitability for untested species before use.
Scientific Background
This gene encodes a serine protease. The protein has been localized in the endoplasmic reticulum and interacts with an alternatively spliced form of mitogen-activated protein kinase 14. The protein has also been localized to the mitochondria with release to the cytosol following apoptotic stimulus. The protein is thought to induce apoptosis by binding the apoptosis inhibitory protein baculoviral IAP repeat-containing 4. Nuclear localization of this protein has also been observed. Alternate splicing of this gene results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Mar 2016]
Safety & Handling
This antibody is validated for Western Blot. Recommended dilutions: WB 1:500
Confirmed reactivity: Human. Other species should be validated by the user.
Conjugate: Unconjugated.
Store as follows: -15°C to -25°C/1 year(Do not lower than -25°C)
Customization & Add-ons: Can't find exactly what you need? Contact us for custom formats, conjugations, bulk quantities, or related products.
