| Field | Specification |
|---|---|
| Target | |
| Alternative names | AGM1;Constant region of heavy chain of IgM;DKFZp686I15196;DKFZp686I15212;FLJ00385;Ig mu chain C region;IGHM;Immunoglobin heavy constant mu;Immunoglobulin mu;MGC104996;MGC52291;MU;VH. |
| Gene ID | |
| Host | |
| Clonality | |
| Reactivity | |
| Applications | |
| Immunogen | Purified recombinant full length of human IgM heavy chain protein expressed in E.coli. |
| Conjugate | |
| Molecular weight | |
| Purification | |
| Cellular localization | |
| Formulation | |
| Storage | |
| Catalog no. (Mfr.) | |
| Main SKU |
Product Overview
U-Blot® Human IgM Mouse Monoclonal Antibody (WM0722) is a mouse monoclonal antibody from UcallM Biosciences Inc, raised against Human IgM. It has been validated for ELISA and reacts with Human.
Validated Applications
| Target | Human IgM |
|---|---|
| Host | Mouse |
| Clonality | Monoclonal |
| Conjugate | Unconjugated |
| Reactivity | Human |
| Applications | ELISA |
| Purification | Affinity Purified |
| Specificity | This antibody detects human IgM proteins. |
| Molecular Weight | Observed: 75 kDa |
| UniProt / Swiss-Prot | P01871 (Human) | P01872 (Mouse) |
Recommended dilutions: ELISA 1:10000-20000
Immunogen / Antigen
Purified recombinant full length of human IgM heavy chain protein expressed in E.coli.
Reactivity Notes
Confirmed cross-reactivity: Human. Confirm suitability for untested species before use.
Scientific Background
Immunoglobulins (Ig) are the antigen recognition molecules of B cells. An Ig molecule is made up of 2 identical heavy chains and 2 identical light chains (see MIM 147200) joined by disulfide bonds so that each heavy chain is linked to a light chain and the 2 heavy chains are linked together. Each Ig heavy chain has an N-terminal variable (V) region containing the antigen-binding site and a C-terminal constant (C) region, encoded by an individual C region gene, that determines the isotype of the antibody and provides effector or signaling functions. The heavy chain V region is encoded by 1 each of 3 types of genes: V genes (see MIM 147070), joining (J) genes (see MIM 147010), and diversity (D) genes (see MIM 146910). The C region genes are clustered downstream of the V region genes within the heavy chain locus on chromosome 14. The IGHM gene encodes the C region of the mu heavy chain, which d
Safety & Handling
This antibody is validated for ELISA. Recommended dilutions: ELISA 1:10000-20000
Confirmed reactivity: Human. Other species should be validated by the user.
Conjugate: Unconjugated.
Store as follows: -15°C to -25°C/1 year(Do not lower than -25°C)
Customization & Add-ons: Can't find exactly what you need? Contact us for custom formats, conjugations, bulk quantities, or related products.
